Product: AOC2 Antibody
Catalog: DF14100
Description: Rabbit polyclonal antibody to AOC2
Application: IHC
Reactivity: Human, Mouse
Mol.Wt.: 84kD; 84kD(Calculated).
Uniprot: O75106

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

AOC2 Antibody detects endogenous levels of total AOC2.
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.


Amine oxidase [copper containing]; Amine oxidase [copper-containing]; Amine oxidase copper containing 2 (retina specific); Amine oxidase copper containing 2; AOC2; AOC2_HUMAN; DAO2; RAO; Retina specific copper amine oxidase; Retina-specific copper amine oxidase; Semicarbazide-sensitive amine oxidase; SSAO;



A synthesized peptide derived from Human AOC2.

O75106 AOC2_HUMAN:

Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis.


Research Backgrounds


Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina.


Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

Subcellular Location:

Cell membrane>Peripheral membrane protein.
Note: Present on the surface of the cells.

Note: Either not translocated to the plasma membrane or below detection level.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in many tissues with much higher expression in retina. Isoform 1 and isoform 2 are expressed in adipose tissue, whereas isoform 1 only seems to be present in thymus, and isoform 2 only in testis.

Subunit Structure:

Homodimer; disulfide-linked (By similarity). Forms a heterodimer with AOC3, in vitro.


Belongs to the copper/topaquinone oxidase family.

Research Fields

· Metabolism > Amino acid metabolism > Glycine, serine and threonine metabolism.

· Metabolism > Amino acid metabolism > Tyrosine metabolism.

· Metabolism > Amino acid metabolism > Phenylalanine metabolism.

· Metabolism > Metabolism of other amino acids > beta-Alanine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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