Product: Fumarylacetoacetate hydrolase Antibody
Catalog: DF13497
Description: Rabbit polyclonal antibody to Fumarylacetoacetate hydrolase
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Bovine
Mol.Wt.: 46kDa; 46kD(Calculated).
Uniprot: P16930
RRID: AB_2846516

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Bovine(88%)
Clonality:
Polyclonal
Specificity:
Fumarylacetoacetate hydrolase Antibody detects endogenous levels of total Fumarylacetoacetate hydrolase.
RRID:
AB_2846516
Cite Format: Affinity Biosciences Cat# DF13497, RRID:AB_2846516.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Beta diketonase; FAA; FAH; Fumarylacetoacetase; Fumarylacetoacetate; Fumarylacetoacetate hydrolase;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P16930 FAAA_HUMAN:

Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues.

Sequence:
MSFIPVAEDSDFPIHNLPYGVFSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEARVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEMAFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSPWVVPMDALMPFAVPNPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFKYMYWTMLQQLTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFLLDGDEVIITGYCQGDGYRIGFGQCAGKVLPALLPS

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
88
Chicken
71
Horse
50
Pig
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P16930 As Substrate

Site PTM Type Enzyme
S2 Acetylation
K79 Acetylation
Y128 Phosphorylation
K144 Ubiquitination
S219 Phosphorylation
K241 Acetylation
K241 Ubiquitination
Y244 Phosphorylation
S309 Phosphorylation
T313 Phosphorylation
T370 Phosphorylation
K371 Ubiquitination
Y395 Phosphorylation
K411 Ubiquitination
S419 Phosphorylation

Research Backgrounds

Tissue Specificity:

Mainly expressed in liver and kidney. Lower levels are also detected in many other tissues.

Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the FAH family.

Research Fields

· Metabolism > Amino acid metabolism > Tyrosine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.