VDAC3 Antibody - #DF12499
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| Product: | VDAC3 Antibody |
| Catalog: | DF12499 |
| Description: | Rabbit polyclonal antibody to VDAC3 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 30 kDa; 31kD(Calculated). |
| Uniprot: | Q9Y277 |
| RRID: | AB_2845304 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF12499, RRID:AB_2845304.
Fold/Unfold
hVDAC3; mVDAC3; Outer mitochondrial membrane protein porin 3; voltage dependent anion channel 3;
Immunogens
- Q9Y277 VDAC3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCNTPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVEFSTSGHAYTDTGKASGNLETKYKVCNYGLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSVGSNVDIDFSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQKVNEKIETSINLAWTAGSNNTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTLSALIDGKNFSAGGHKVGLGFELEA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9Y277 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Ubiquitination | Uniprot | ||
| C2 | Acetylation | Uniprot | |
| T4 | Phosphorylation | Uniprot | |
| T6 | Phosphorylation | Uniprot | |
| Y7 | Phosphorylation | Uniprot | |
| K12 | Acetylation | Uniprot | |
| K12 | Ubiquitination | Uniprot | |
| K15 | Acetylation | Uniprot | |
| K15 | Ubiquitination | Uniprot | |
| K20 | Acetylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| Y22 | Phosphorylation | Uniprot | |
| K28 | Acetylation | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| C36 | S-Nitrosylation | Uniprot | |
| S44 | Phosphorylation | Uniprot | |
| Y48 | Phosphorylation | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| K53 | Ubiquitination | Uniprot | |
| K61 | Acetylation | Uniprot | |
| K61 | Ubiquitination | Uniprot | |
| K63 | Acetylation | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| C65 | S-Nitrosylation | Uniprot | |
| Y67 | Phosphorylation | Uniprot | |
| T70 | Phosphorylation | Uniprot | |
| K90 | Acetylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| K96 | Acetylation | Uniprot | |
| T107 | Phosphorylation | Uniprot | |
| K109 | Acetylation | Uniprot | |
| K109 | Ubiquitination | Uniprot | |
| K110 | Acetylation | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K113 | Acetylation | Uniprot | |
| K115 | Acetylation | Uniprot | |
| K119 | Acetylation | Uniprot | |
| K163 | Acetylation | Uniprot | |
| K163 | Ubiquitination | Uniprot | |
| Y173 | Phosphorylation | Uniprot | |
| K174 | Acetylation | Uniprot | |
| Y195 | Phosphorylation | Uniprot | |
| K197 | Ubiquitination | Uniprot | |
| K224 | Acetylation | Uniprot | |
| Y247 | Phosphorylation | Uniprot | |
| T250 | Phosphorylation | Uniprot | |
| S260 | Phosphorylation | Uniprot | |
| K266 | Acetylation | Uniprot | |
| K266 | Ubiquitination | Uniprot | |
| K274 | Ubiquitination | Uniprot |
Research Backgrounds
Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
Mitochondrion outer membrane.
Widely expressed. Highest in testis.
Consists mainly of a membrane-spanning beta-barrel formed by 19 beta-strands.
Belongs to the eukaryotic mitochondrial porin family.
Research Fields
· Cellular Processes > Cell growth and death > Ferroptosis. (View pathway)
· Cellular Processes > Cell growth and death > Necroptosis. (View pathway)
· Cellular Processes > Cell growth and death > Cellular senescence. (View pathway)
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Human Diseases > Infectious diseases: Viral > Hepatitis B.
· Human Diseases > Infectious diseases: Viral > HTLV-I infection.
· Human Diseases > Cancers: Overview > Viral carcinogenesis.
· Organismal Systems > Immune system > NOD-like receptor signaling pathway. (View pathway)
· Organismal Systems > Digestive system > Cholesterol metabolism.
References
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