LDHA Antibody - #AF7672
Product: | LDHA Antibody |
Catalog: | AF7672 |
Description: | Rabbit polyclonal antibody to LDHA |
Application: | WB IF/ICC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Sheep, Rabbit |
Mol.Wt.: | 37kDa; 37kD(Calculated). |
Uniprot: | P00338 |
RRID: | AB_2844036 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF7672, RRID:AB_2844036.
Fold/Unfold
Cell proliferation-inducing gene 19 protein; L lactate dehydrogenase A chain; Lactate dehydrogenase A; LDH A; LDH M; LDH muscle subunit; LDH1; LDH5; LDHA; PIG 19; PIG19; Renal carcinoma antigen NY-REN-59;
Immunogens
- P00338 LDHA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATLKDQLIYNLLKEEQTPQNKITVVGVGAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSGKDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPVDILTYVAWKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDSSVPVWSGMNVAGVSLKTLHPDLGTDKDKEQWKEVHKQVVESAYEVIKLKGYTSWAIGLSVADLAESIMKNLRRVHPVSTMIKGLYGIKDDVFLSVPCILGQNGISDLVKVTLTSEEEARLKKSADTLWGIQKELQF
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P00338 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
A2 | Acetylation | Uniprot | |
T3 | Phosphorylation | Uniprot | |
K5 | Acetylation | Uniprot | |
K5 | Methylation | Uniprot | |
K5 | Ubiquitination | Uniprot | |
Y10 | Phosphorylation | P11362 (FGFR1) , P04626 (ERBB2) , P12931 (SRC) | Uniprot |
K14 | Acetylation | Uniprot | |
K14 | Sumoylation | Uniprot | |
K14 | Ubiquitination | Uniprot | |
T18 | Phosphorylation | Uniprot | |
K22 | Acetylation | Uniprot | |
K57 | Acetylation | Uniprot | |
K57 | Ubiquitination | Uniprot | |
K59 | Ubiquitination | Uniprot | |
T74 | Phosphorylation | Uniprot | |
K76 | Ubiquitination | Uniprot | |
K81 | Acetylation | Uniprot | |
K81 | Ubiquitination | Uniprot | |
Y83 | Phosphorylation | P11362 (FGFR1) | Uniprot |
S89 | Phosphorylation | Uniprot | |
K90 | Ubiquitination | Uniprot | |
T95 | Phosphorylation | Uniprot | |
K118 | Acetylation | Uniprot | |
K118 | Methylation | Uniprot | |
K118 | Ubiquitination | Uniprot | |
K126 | Acetylation | Uniprot | |
K126 | Ubiquitination | Uniprot | |
Y127 | Phosphorylation | Uniprot | |
S128 | Phosphorylation | Uniprot | |
K132 | Acetylation | Uniprot | |
K132 | Ubiquitination | Uniprot | |
Y145 | Phosphorylation | Uniprot | |
K155 | Ubiquitination | Uniprot | |
R157 | Methylation | Uniprot | |
S161 | Phosphorylation | Uniprot | |
S167 | Phosphorylation | Uniprot | |
R169 | Methylation | Uniprot | |
Y172 | Phosphorylation | Uniprot | |
S184 | Phosphorylation | Uniprot | |
K212 | Ubiquitination | Uniprot | |
K222 | Acetylation | Uniprot | |
K222 | Ubiquitination | Uniprot | |
K224 | Acetylation | Uniprot | |
K224 | Ubiquitination | Uniprot | |
K228 | Acetylation | Uniprot | |
K228 | Ubiquitination | Uniprot | |
K232 | Acetylation | Uniprot | |
K232 | Ubiquitination | Uniprot | |
S237 | Phosphorylation | Uniprot | |
Y239 | Phosphorylation | Uniprot | |
K243 | Acetylation | Uniprot | |
K243 | Ubiquitination | Uniprot | |
K245 | Ubiquitination | Uniprot | |
T248 | Phosphorylation | P06493 (CDK1) | Uniprot |
S249 | Phosphorylation | Uniprot | |
R269 | Methylation | Uniprot | |
K278 | Acetylation | Uniprot | |
K278 | Methylation | Uniprot | |
K278 | Ubiquitination | Uniprot | |
K284 | Ubiquitination | Uniprot | |
K305 | Ubiquitination | Uniprot | |
T309 | Phosphorylation | Uniprot | |
S310 | Phosphorylation | Uniprot | |
K317 | Ubiquitination | Uniprot | |
K318 | Acetylation | Uniprot | |
K318 | Ubiquitination | Uniprot | |
S319 | Phosphorylation | Uniprot | |
T322 | Phosphorylation | Uniprot | |
K328 | Acetylation | Uniprot | |
K328 | Sumoylation | Uniprot | |
K328 | Ubiquitination | Uniprot |
Research Backgrounds
ISGylated.
Cytoplasm.
Homotetramer.
Belongs to the LDH/MDH superfamily. LDH family.
Research Fields
· Environmental Information Processing > Signal transduction > HIF-1 signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Central carbon metabolism in cancer. (View pathway)
· Metabolism > Carbohydrate metabolism > Glycolysis / Gluconeogenesis.
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Carbohydrate metabolism > Pyruvate metabolism.
· Metabolism > Carbohydrate metabolism > Propanoate metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Endocrine system > Glucagon signaling pathway.
References
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For Research Use Only.
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