Phospho-HPD (Thr382) Antibody - #AF8609
| Product: | Phospho-HPD (Thr382) Antibody |
| Catalog: | AF8609 |
| Description: | Rabbit polyclonal antibody to Phospho-HPD (Thr382) |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Rabbit |
| Mol.Wt.: | 45 kDa; 45kD(Calculated). |
| Uniprot: | P32754 |
| RRID: | AB_2843459 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF8609, RRID:AB_2843459.
Fold/Unfold
4 HPPD; 4 hydroxyphenylpyruvate dioxygenase; 4 hydroxyphenylpyruvic acid oxidase; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; GLOD3; glyoxalase domain containing 3; HPD; HPPD_HUMAN; HPPDase; PPD;
Immunogens
- P32754 HPPD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQNLRGNLTNMETNGVVPGM
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P32754 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T2 | Acetylation | Uniprot | |
| Y4 | Phosphorylation | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| Y105 | Phosphorylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| S211 | Phosphorylation | Uniprot | |
| Y221 | Phosphorylation | Uniprot | |
| S222 | Phosphorylation | Uniprot | |
| S223 | Phosphorylation | Uniprot | |
| S226 | Phosphorylation | Uniprot | |
| Y232 | Phosphorylation | Uniprot | |
| K247 | Acetylation | Uniprot | |
| K249 | Ubiquitination | Uniprot | |
| S290 | Phosphorylation | Uniprot | |
| Y295 | Phosphorylation | Uniprot | |
| Y296 | Phosphorylation | Uniprot | |
| K297 | Ubiquitination | Uniprot | |
| K311 | Ubiquitination | Uniprot | |
| T382 | Phosphorylation | Calculation |
Research Backgrounds
Key enzyme in the degradation of tyrosine.
Homodimer.
Belongs to the 4HPPD family.
Research Fields
· Metabolism > Metabolism of cofactors and vitamins > Ubiquinone and other terpenoid-quinone biosynthesis.
· Metabolism > Amino acid metabolism > Tyrosine metabolism.
· Metabolism > Amino acid metabolism > Phenylalanine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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