TAT Antibody - #DF8469
| Product: | TAT Antibody |
| Catalog: | DF8469 |
| Description: | Rabbit polyclonal antibody to TAT |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 140 kDa; 50kD(Calculated). |
| Uniprot: | P17735 |
| RRID: | AB_2841701 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF8469, RRID:AB_2841701.
Fold/Unfold
ATTY_HUMAN; L-tyrosine:2-oxoglutarate aminotransferase; TAT; Tyrosine aminotransferase; Tyrosine aminotransferase, cytosolic;
Immunogens
- P17735 ATTY_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDPYMIQMSSKGNLPSILDVHVNVGGRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIVDNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAIPGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFIRVVITVPEVMMLEACSRIQEFCEQHYHCAEGSQEECDK
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P17735 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S10 | Phosphorylation | Uniprot | |
| K33 | Acetylation | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| T321 | Phosphorylation | Uniprot | |
| Y442 | Phosphorylation | Uniprot | |
| S448 | Phosphorylation | Uniprot |
Research Backgrounds
Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine.
Homodimer.
Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
Research Fields
· Metabolism > Metabolism of cofactors and vitamins > Ubiquinone and other terpenoid-quinone biosynthesis.
· Metabolism > Amino acid metabolism > Cysteine and methionine metabolism.
· Metabolism > Amino acid metabolism > Tyrosine metabolism.
· Metabolism > Amino acid metabolism > Phenylalanine metabolism.
· Metabolism > Amino acid metabolism > Phenylalanine, tyrosine and tryptophan biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Biosynthesis of amino acids.
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