TNAP2 Antibody - #AF0630
(3)
| Product: | TNAP2 Antibody |
| Catalog: | AF0630 |
| Description: | Rabbit polyclonal antibody to TNAP2 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Monkey |
| Prediction: | Horse, Rabbit, Dog |
| Mol.Wt.: | 72kDa; 73kD(Calculated). |
| Uniprot: | Q03169 |
| RRID: | AB_2834244 |
Product Info
Source:
Rabbit
Application:
IHC 1:50-1:200, IF/ICC 1:100-1:500, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Reactivity:
Human,Mouse,Monkey
Prediction:
Horse(100%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
TNAP2 Antibody detects endogenous levels of total TNAP2.
RRID:
AB_2834244
Cite Format: Affinity Biosciences Cat# AF0630, RRID:AB_2834244.
Cite Format: Affinity Biosciences Cat# AF0630, RRID:AB_2834244.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:
Fold/Unfold
B94; EXOC3L3; exocyst complex component 3-like 3; Primary response gene B94 protein; TNAP2_HUMAN; TNF alpha-induced protein 2; Tnfaip2; tumor necrosis factor alpha induced protein 2; Tumor necrosis factor alpha-induced protein 2; tumor necrosis factor, alpha-induced protein 2 antibody;
Immunogens
Immunogen:
Uniprot:
Gene(ID):
Description:
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of this gene was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that this gene may be a retinoic acid target gene in acute promyelocytic leukemia.
Sequence:
- Q03169 TNAP2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSEASSEDLVPPLEAGAAPYREEEEAAKKKKEKKKKSKGLANVFCVFTKGKKKKGQPSSAEPEDAAGSRQGLDGPPPTVEELKAALERGQLEAARPLLALERELAAAAAAGGVSEEELVRRQSKVEALYELLRDQVLGVLRRPLEAPPERLRQALAVVAEQEREDRQAAAAGPGTSGLAATRPRRWLQLWRRGVAEAAEERMGQRPAAGAEVPESVFLHLGRTMKEDLEAVVERLKPLFPAEFGVVAAYAESYHQHFAAHLAAVAQFELCERDTYMLLLWVQNLYPNDIINSPKLVGELQGMGLGSLLPPRQIRLLEATFLSSEAANVRELMDRALELEARRWAEDVPPQRLDGHCHSELAIDIIQITSQAQAKAESITLDLGSQIKRVLLVELPAFLRSYQRAFNEFLERGKQLTNYRANVIANINNCLSFRMSMEQNWQVPQDTLSLLLGPLGELKSHGFDTLLQNLHEDLKPLFKRFTHTRWAAPVETLENIIATVDTRLPEFSELQGCFREELMEALHLHLVKEYIIQLSKGRLVLKTAEQQQQLAGYILANADTIQHFCTQHGSPATWLQPALPTLAEIIRLQDPSAIKIEVATYATCYPDFSKGHLSAILAIKGNLSNSEVKRIRSILDVSMGAQEPSRPLFSLIKVG
Predictions
Predictions:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Horse
100
Dog
100
Rabbit
100
Pig
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q03169 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| S37 | Phosphorylation | Uniprot | |
| S68 | Phosphorylation | Uniprot | |
| K83 | Ubiquitination | Uniprot | |
| S114 | Phosphorylation | Uniprot | |
| S123 | Phosphorylation | Uniprot | |
| K124 | Ubiquitination | Uniprot | |
| K478 | Acetylation | Uniprot | |
| Y529 | Phosphorylation | Uniprot | |
| T599 | Phosphorylation | Uniprot | |
| T602 | Phosphorylation | Uniprot | |
| K628 | Ubiquitination | Uniprot | |
| S632 | Phosphorylation | Uniprot | |
| K652 | Ubiquitination | Uniprot |
Research Backgrounds
Function:
May play a role as a mediator of inflammation and angiogenesis.
Family&Domains:
Belongs to the SEC6 family.
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For Research Use Only.
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