TTF2 Antibody - #AF0737
| Product: | TTF2 Antibody |
| Catalog: | AF0737 |
| Description: | Rabbit polyclonal antibody to TTF2 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine |
| Mol.Wt.: | 34kDa; 38kD(Calculated). |
| Uniprot: | O00358 |
| RRID: | AB_2834169 |
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Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF0737, RRID:AB_2834169.
Fold/Unfold
FKH L15; FKHL 15; FKHL15; Forkhead (Drosophila) like 15; Forkhead box E1; Forkhead box E2; Forkhead box protein E1; Forkhead box protein E2; Forkhead drosophila homolog like 15; Forkhead like 15; Forkhead related protein FKHL 15; Forkhead related protein FKHL15; Forkhead-related protein FKHL15; FOX E1; FOX E2; FOXE 1; FOXE 2; FOXE1; FOXE1_HUMAN; FOXE2; HFKH 4; HFKH4; HFKL 5; HFKL5; HNF-3/fork head-like protein 5; Thyroid transcription factor 2; TITF 2; TITF2; TTF 2; TTF-2; TTF2;
Immunogens
Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.
- O00358 FOXE1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYIALIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGRPGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAAAIFPGAVPAARPPYPGAVYAGYAPPSLAAPPPVYYPAASPGPCRVFGLVPERPLSPELGPAPSGPGGSCAFASAGAPATTTGYQPAGCTGARPANPSAYAAAYAGPDGAYPQGAGSAIFAAAGRLAGPASPPAGGSSGGVETTVDFYGRTSPGQFGALGACYNPGGQLGGASAGAYHARHAAAYPGGIDRFVSAM
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00358 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T2 | Phosphorylation | Uniprot | |
| S5 | Phosphorylation | Uniprot | |
| K19 | Sumoylation | Uniprot | |
| T36 | Phosphorylation | Uniprot | |
| K46 | Acetylation | Uniprot |
Research Backgrounds
Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.
Phosphorylated.
Nucleus.
Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.
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