NPY4R Antibody - #DF2823
| Product: | NPY4R Antibody |
| Catalog: | DF2823 |
| Description: | Rabbit polyclonal antibody to NPY4R |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human |
| Mol.Wt.: | 42 kDa; 42kD(Calculated). |
| Uniprot: | P50391 |
| RRID: | AB_2840029 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2823, RRID:AB_2840029.
Fold/Unfold
MGC116897; Neuropeptide Y receptor type 4; NPY4 R; NPY4-R; Npy4r; NPY4R_HUMAN; Pancreatic polypeptide receptor 1; PP 1; PP1; PPY R1; PPYR 1; PPYR1; Y4;
Immunogens
Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine.
- P50391 NPY4R_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRRLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSNPI
PTMs - P50391 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T3 | Phosphorylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| K190 | Ubiquitination | Uniprot | |
| K334 | Ubiquitination | Uniprot | |
| K363 | Ubiquitination | Uniprot |
Research Backgrounds
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PP, PP (2-36) and [Ile-31, Gln-34] PP > [Pro-34] PYY > PYY and [Leu-31, Pro-34] NPY > NPY > PYY (3-36) and NPY (2-36) > PP (13-36) > PP (31-36) > NPY free acid.
Cell membrane>Multi-pass membrane protein.
Highest levels found in brain, coronary artery and ileum. Low levels in pancreas and kidney. Detected in colon and small intestine.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
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