SS3R Antibody | Affinity Biosciences

1/1

Western blot analysis of extracts from Rat brain, using SS3R Antibody at 1/1000 dilution.

Product:	SS3R Antibody
Catalog:	DF2778
Description:	Rabbit polyclonal antibody to SS3R
Application:	WB IHC
Reactivity:	Human
Prediction:	Rat, Pig, Bovine, Sheep
Mol.Wt.:	46 kDa; 46kD(Calculated).
Uniprot:	P32745
RRID:	AB_2839984

View similar products>>

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors

Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Prediction:

Rat(%), Pig(82%), Bovine(100%), Sheep(100%)

Clonality:

Polyclonal

Specificity:

SS3R Antibody detects endogenous levels of total SS3R.

RRID:

AB_2839984
Cite Format: Affinity Biosciences Cat# DF2778, RRID:AB_2839984.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

OTTHUMP00000028737; Smstr 3; Smstr3; Somatostatin receptor subtype 3; Somatostatin receptor type 3; SS 3R; SS-3-R; SS3-R; SS3R; SSR 28; SSR-28; SSR28; SSR3_HUMAN; Sst 3; Sst3; SSTR 3; SSTR3;

Immunogens

Immunogen:

Uniprot:

P32745(SSR3_HUMAN) >>Visit HPA database.

Gene(ID):

SSTR3(6753)

Expression:

P32745 SSR3_HUMAN:

Brain, pituitary and pancreas.

Description:

Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.

Sequence:

P32745 SSR3_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MDMLHPSSVSTTSEPENASSAWPPDATLGNVSAGPSPAGLAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALADELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSVDRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMSTCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRRVWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEPAFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVLLRPSRRVRSQEPTVGPPEKTEEEDEEEEDGEESREGGKGKEMNGRVSQITQPGTSGQERPPSRVASKEQQLLPQEASTGEKSSTMRISYL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Bovine

100

Sheep

100

Pig

Horse

Dog

Xenopus

Zebrafish

Chicken

Rabbit

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P32745 As Substrate

P32745

Site	PTM Type	Source
R71	Methylation	Uniprot
Y142	Phosphorylation	Uniprot
Y303	Phosphorylation	Uniprot
S332	Phosphorylation	Uniprot
S337	Phosphorylation	Uniprot
T341	Phosphorylation	Uniprot
T348	Phosphorylation	Uniprot
S361	Phosphorylation	Uniprot

Research Backgrounds

P32745_SSR3_HUMAN

Function:

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.

PTMs:

Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity).

Subcellular Location:

Cell membrane>Multi-pass membrane protein.
Note: Internalized into endoplasmic vesicles upon somatostatin-stimulation.

Tissue Specificity:

Brain, pituitary and pancreas.

Subunit Structure:

Homodimer and heterodimer with SSTR2. Heterodimerization with SSTR2 inactivates SSTR3 receptor function (By similarity).

Family&Domains:

Belongs to the G-protein coupled receptor 1 family.

Research Fields

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.

SS3R Antibody - #DF2778