Product: GPR92/GPR93 Antibody
Catalog: DF2774
Description: Rabbit polyclonal antibody to GPR92/GPR93
Application: WB IHC IF/ICC
Reactivity: Human
Prediction: Bovine
Mol.Wt.: Predicted band size : 41 kDa,Observed band size : 41 kDa; 41kD(Calculated).
Uniprot: Q9H1C0
RRID: AB_2839980

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Bovine(80%)
Clonality:
Polyclonal
Specificity:
GPR92/GPR93 Antibody detects endogenous levels of total GPR92/GPR93.
RRID:
AB_2839980
Cite Format: Affinity Biosciences Cat# DF2774, RRID:AB_2839980.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

G protein coupled receptor 92; G-protein coupled receptor 92; G-protein coupled receptor 93; GPR 92; GPR 93; GPR92; GPR93; KPG 010; LPA receptor 5; LPA-5; Lpar5; LPAR5_HUMAN; Lysophosphatidic acid receptor 5; Probable G protein coupled receptor 92; Putative G protein coupled receptor 92;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9H1C0 LPAR5_HUMAN:

Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.

Description:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.
Sequence:
MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
80
Pig
0
Horse
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H1C0 As Substrate

Site PTM Type Enzyme
Y29 Phosphorylation
S268 Phosphorylation
S332 Phosphorylation

Research Backgrounds

Function:

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.

Family&Domains:

Belongs to the G-protein coupled receptor 1 family.

Research Fields

· Environmental Information Processing > Signal transduction > Rap1 signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Human Diseases > Cancers: Overview > Pathways in cancer.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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