GPR8 Antibody - #DF2764
| Product: | GPR8 Antibody |
| Catalog: | DF2764 |
| Description: | Rabbit polyclonal antibody to GPR8 |
| Application: | WB IHC |
| Reactivity: | Human, Mouse, Rat, Monkey |
| Mol.Wt.: | 37 kDa; 37kD(Calculated). |
| Uniprot: | P48146 |
| RRID: | AB_2839970 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2764, RRID:AB_2839970.
Fold/Unfold
G protein coupled receptor 8; G protein coupled receptor 8; GPR8; Neuropeptides B/W receptor type 2; NPBWR2;
Immunogens
Detected at high levels in caudate nucleus, hyppocampus and amygdala; at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes.
- P48146 NPBW2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQAAGHPEPLDSRGSFSLPTMGANVSQDNGTGHNATFSEPLPFLYVLLPAVYSGICAVGLTGNTAVILVILRAPKMKTVTNVFILNLAVADGLFTLVLPVNIAEHLLQYWPFGELLCKLVLAVDHYNIFSSIYFLAVMSVDRYLVVLATVRSRHMPWRTYRGAKVASLCVWLGVTVLVLPFFSFAGVYSNELQVPSCGLSFPWPEQVWFKASRVYTLVLGFVLPVCTICVLYTDLLRRLRAVRLRSGAKALGKARRKVTVLVLVVLAVCLLCWTPFHLASVVALTTDLPQTPLVISMSYVITSLSYANSCLNPFLYAFLDDNFRKNFRSILRC
PTMs - P48146 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y126 | Phosphorylation | Uniprot | |
| Y133 | Phosphorylation | Uniprot | |
| Y143 | Phosphorylation | Uniprot |
Research Backgrounds
Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals.
Cell membrane>Multi-pass membrane protein.
Detected at high levels in caudate nucleus, hyppocampus and amygdala; at moderate levels in the adult brain, thalamus, parietal cortex, pituitary gland, adrenal gland and lymph nodes.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
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