OGR1/GPR68 Antibody - #DF2759
| Product: | OGR1/GPR68 Antibody |
| Catalog: | DF2759 |
| Description: | Rabbit polyclonal antibody to OGR1/GPR68 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 40~70 kD; 41kD(Calculated). |
| Uniprot: | Q15743 |
| RRID: | AB_2839965 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2759, RRID:AB_2839965.
Fold/Unfold
G protein coupled receptor 68; G-protein coupled receptor 68; GPR 12A; GPR 68; GPR12A; Gpr68; MGC111379; MGC156983; OGR 1; OGR-1; OGR1; OGR1_HUMAN; Ovarian cancer G protein coupled receptor 1; Ovarian cancer G-protein coupled receptor 1; Sphingosylphosphorylcholine receptor;
Immunogens
Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.
- Q15743 OGR1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGNITADNSSMSCTIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTVADLFYICSLPFWLQYVLQHDNWSHGDLSCQVCGILLYENIYISVGFLCCISVDRYLAVAHPFRFHQFRTLKAAVGVSVVIWAKELLTSIYFLMHEEVIEDENQHRVCFEHYPIQAWQRAINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSVWEASCDFAKGVFNAYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAFLTCSRTGRAREAYPLGAPEASGKSGAQGEEPELLTKLHPAFQTPNSPGSGGFPTGRLA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q15743 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y187 | Phosphorylation | Uniprot | |
| Y188 | Phosphorylation | Uniprot | |
| Y244 | Phosphorylation | Uniprot | |
| S328 | Phosphorylation | Uniprot | |
| S331 | Phosphorylation | Uniprot | |
| S353 | Phosphorylation | Uniprot |
Research Backgrounds
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer (By similarity).
Cell membrane>Multi-pass membrane protein.
Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.
Belongs to the G-protein coupled receptor 1 family.
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