BCL2L13 Antibody - #DF2649

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Product: BCL2L13 Antibody
Catalog: DF2649
Description: Rabbit polyclonal antibody to BCL2L13
Application: WB IHC
Reactivity: Human
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 50 kDa.; 53kD(Calculated).
Uniprot: Q9BXK5
RRID: AB_2839855

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Pig(88%), Bovine(88%), Horse(100%), Sheep(88%), Rabbit(100%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
BCL2L13 Antibody detects endogenous levels of total BCL2L13.
RRID:
AB_2839855
Cite Format: Affinity Biosciences Cat# DF2649, RRID:AB_2839855.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Apoptosis facilitator; B2L13_HUMAN; Bcl 2 like 13; Bcl 2 like 13 protein; Bcl-2-like protein 13; Bcl-rambo; BCL2 like 13 apoptosis facilitator; BCL2 like 13; Bcl2 like 13 protein; Bcl2-L-13; BCL2L13; MIL 1; MIL1; MIL1 protein; Protein Mil1;

Immunogens

Immunogen:
Uniprot:

Q9BXK5(B2L13_HUMAN) >>Visit HPA database.

Gene(ID):
BCL2L13(23786)
Expression:
Q9BXK5 B2L13_HUMAN:

Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.

Description:
May promote the activation of caspase-3 and apoptosis.
Sequence:
MASSSTVPLGFHYETKYVVLSYLGLLSQEKLQEQHLSSPQGVQLDIASQSLDQEILLKVKTEIEEELKSLDKEISEAFTSTGFDRHTSPVFSPANPESSMEDCLAHLGEKVSQELKEPLHKALQMLLSQPVTYQAFRECTLETTVHASGWNKILVPLVLLRQMLLELTRRGQEPLSALLQFGVTYLEDYSAEYIIQQGGWGTVFSLESEEEEYPGITAEDSNDIYILPSDNSGQVSPPESPTVTTSWQSESLPVSLSASQSWHTESLPVSLGPESWQQIAMDPEEVKSLDSNGAGEKSENNSSNSDIVHVEKEEVPEGMEEAAVASVVLPARELQEALPEAPAPLLPHITATSLLGTREPDTEVITVEKSSPATSLFVELDEEEVKAATTEPTEVEEVVPALEPTETLLSEKEINAREESLVEELSPASEKKPVPPSEGKSRLSPAGEMKPMPLSEGKSILLFGGAAAVAILAVAIGVALALRKK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Dog
100
Chicken
100
Rabbit
100
Pig
88
Bovine
88
Sheep
88
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BXK5 As Substrate

Site PTM Type Enzyme
S3 Phosphorylation
S37 Phosphorylation
S38 Phosphorylation
K60 Ubiquitination
K68 Ubiquitination
K72 Ubiquitination
K110 Ubiquitination
K116 Ubiquitination
T168 Phosphorylation
S259 Phosphorylation
S261 Phosphorylation
S270 Phosphorylation
S275 Phosphorylation
S288 Phosphorylation
S291 Phosphorylation
S298 Phosphorylation
S302 Phosphorylation
S303 Phosphorylation
S305 Phosphorylation
S326 Phosphorylation
T352 Phosphorylation
S370 Phosphorylation
S371 Phosphorylation
T374 Phosphorylation
S375 Phosphorylation
S410 Phosphorylation
K412 Ubiquitination
S420 Phosphorylation
S426 Phosphorylation
S429 Phosphorylation
S437 Phosphorylation
K440 Ubiquitination
S441 Phosphorylation
S444 Phosphorylation
K450 Ubiquitination

Research Backgrounds

Function:

May promote the activation of caspase-3 and apoptosis.

Subcellular Location:

Mitochondrion membrane>Single-pass membrane protein. Nucleus.

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Ubiquitous, with the highest levels of expression in heart, placenta and pancreas.

Subunit Structure:

Monomer.

Family&Domains:

Belongs to the Bcl-2 family.

Research Fields

· Human Diseases > Infectious diseases: Bacterial > Legionellosis.

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