RASAL2 Antibody - #DF2644

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Product: RASAL2 Antibody
Catalog: DF2644
Description: Rabbit polyclonal antibody to RASAL2
Application: WB IHC
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Dog, Chicken
Mol.Wt.: 129 kDa; 129kD(Calculated).
Uniprot: Q9UJF2
RRID: AB_2839850

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
RASAL2 Antibody detects endogenous levels of total RASAL2.
RRID:
AB_2839850
Cite Format: Affinity Biosciences Cat# DF2644, RRID:AB_2839850.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

nGAP; NGAP_HUMAN; Ras GTPase-activating protein nGAP; Ras protein activator like 1; RAS protein activator-like 2; RASAL2;

Immunogens

Immunogen:
Uniprot:

Q9UJF2(NGAP_HUMAN) >>Visit HPA database.

Gene(ID):
RASAL2(9462)
Description:
Inhibitory regulator of the Ras-cyclic AMP pathway.
Sequence:
MQTPEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDERESSLPNGRSVSLMDLQDTHAAQVEHASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSFQNPVYHLNNPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTVPDRHIPLALPRQNSTGQAQIRKVDQGGLGARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Zebrafish
73
Xenopus
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9UJF2 As Substrate

Site PTM Type Enzyme
S11 Phosphorylation
S16 Phosphorylation
S18 Phosphorylation
T20 Phosphorylation
K25 Acetylation
S28 Phosphorylation
T31 Phosphorylation
T34 Phosphorylation
S35 Phosphorylation
K38 Acetylation
S44 Phosphorylation
S56 Phosphorylation
T64 Phosphorylation
S65 Phosphorylation
S70 Phosphorylation
S89 Phosphorylation
S92 Phosphorylation
S95 Phosphorylation
S98 Phosphorylation
S139 Phosphorylation
Y246 Phosphorylation
K278 Ubiquitination
S283 Phosphorylation
S355 Phosphorylation
K376 Ubiquitination
Y381 Phosphorylation
Y389 Phosphorylation
S558 Phosphorylation
Y566 Phosphorylation
K614 Ubiquitination
T617 Phosphorylation
T620 Phosphorylation
T630 Phosphorylation
S634 Phosphorylation
S635 Phosphorylation
S639 Phosphorylation
S641 Phosphorylation
S644 Phosphorylation
K660 Ubiquitination
K662 Methylation
K662 Ubiquitination
S663 Phosphorylation
S665 Phosphorylation
S671 Phosphorylation
Y672 Phosphorylation
S700 Phosphorylation
T734 Phosphorylation
S736 Phosphorylation
S739 Phosphorylation
T741 Phosphorylation
S745 Phosphorylation
T755 Phosphorylation
S758 Phosphorylation
S780 Phosphorylation
Y786 Phosphorylation
S803 Phosphorylation
S830 Phosphorylation
S838 Phosphorylation
S841 Phosphorylation
T849 Phosphorylation
S864 Phosphorylation
T865 Phosphorylation
K872 Acetylation
S887 Phosphorylation
S891 Phosphorylation
S893 Phosphorylation
S896 Phosphorylation
S899 Phosphorylation
S916 Phosphorylation
S918 Phosphorylation
S922 Phosphorylation
S923 Phosphorylation
S924 Phosphorylation
S925 Phosphorylation
S928 Phosphorylation
T941 Phosphorylation
S946 Phosphorylation
S954 Phosphorylation
Y1010 Phosphorylation
K1080 Acetylation
S1091 Phosphorylation
S1111 Phosphorylation
S1119 Phosphorylation
K1135 Methylation

Research Backgrounds

Function:

Inhibitory regulator of the Ras-cyclic AMP pathway.

Research Fields

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

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