Cytochrome P450 3A43 Antibody - #DF2617
| Product: | Cytochrome P450 3A43 Antibody |
| Catalog: | DF2617 |
| Description: | Rabbit polyclonal antibody to Cytochrome P450 3A43 |
| Application: | WB IHC |
| Reactivity: | Human |
| Mol.Wt.: | 58kD(Calculated). |
| Uniprot: | Q9HB50 | Q9HB55 |
| RRID: | AB_2839823 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2617, RRID:AB_2839823.
Fold/Unfold
Cytochrome P450 family 3 subfamily A polypeptide 43; Cytochrome P450 polypeptide 43; Cytochrome P450 subfamily IIIA polypeptide 43; MGC119315; MGC119316; CYP3A43;
Immunogens
A synthesized peptide derived from human Cytochrome P450 3A43, corresponding to a region within C-terminal amino acids.
Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.
- Q9HB55 CP343_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDLIPNFAMETWVLVATSLVLLYIYGTHSHKLFKKLGIPGPTPLPFLGTILFYLRGLWNFDRECNEKYGEMWGLYEGQQPMLVIMDPDMIKTVLVKECYSVFTNQMPLGPMGFLKSALSFAEDEEWKRIRTLLSPAFTSVKFKEMVPIISQCGDMLVRSLRQEAENSKSINLKDFFGAYTMDVITGTLFGVNLDSLNNPQDPFLKNMKKLLKLDFLDPFLLLISLFPFLTPVFEALNIGLFPKDVTHFLKNSIERMKESRLKDKQKHRVDFFQQMIDSQNSKETKSHKALSDLELVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLPNKAPVTYDALVQMEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPEKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKPCKETQIPLKLDNLPILQPEKPIVLKVHLRDGITSGP
PTMs - Q9HB50/Q9HB55 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y75 | Phosphorylation | Uniprot | |
| T450 | Phosphorylation | Uniprot |
Research Backgrounds
Exhibits low testosterone 6-beta-hydroxylase activity.
Endoplasmic reticulum membrane>Peripheral membrane protein. Microsome membrane>Peripheral membrane protein.
Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.
Belongs to the cytochrome P450 family.
Research Fields
· Human Diseases > Cancers: Overview > Chemical carcinogenesis.
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