Product: BCL7B Antibody
Catalog: DF2586
Description: Rabbit polyclonal antibody to BCL7B
Application: WB
Reactivity: Human, Mouse
Prediction: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
Mol.Wt.: 22 kDa; 22kD(Calculated).
Uniprot: Q9BQE9
RRID: AB_2839792

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 100ul $280 In stock
 200ul $350 In stock

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Pig(100%), Bovine(100%), Horse(83%), Sheep(100%), Rabbit(92%), Dog(100%), Chicken(83%)
Clonality:
Polyclonal
Specificity:
BCL7B Antibody detects endogenous levels of total BCL7B.
RRID:
AB_2839792
Cite Format: Affinity Biosciences Cat# DF2586, RRID:AB_2839792.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

B cell CLL/lymphoma 7 protein family member B; B cell CLL/lymphoma 7B; B-cell CLL/lymphoma 7 protein family member B; BCL 7B; BCL7B; BCL7B_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9BQE9 BCL7B_HUMAN:

Ubiquitous.

Description:
May play a role in lung tumor development or progression.
Sequence:
MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Rabbit
92
Horse
83
Chicken
83
Xenopus
67
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BQE9 As Substrate

Site PTM Type Enzyme
K27 Ubiquitination
K34 Ubiquitination
T41 Phosphorylation
S107 Phosphorylation
S108 Phosphorylation
T109 Phosphorylation
S112 Phosphorylation
S114 Phosphorylation
S118 Phosphorylation
S120 Phosphorylation
S122 Phosphorylation
T126 Phosphorylation
S127 Phosphorylation
T131 Phosphorylation
S134 Phosphorylation
S180 Phosphorylation
K186 Ubiquitination
C189 S-Nitrosylation
T194 Phosphorylation
S200 Phosphorylation

Research Backgrounds

Function:

Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression (By similarity).

Tissue Specificity:

Ubiquitous.

Family&Domains:

Belongs to the BCL7 family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.