IL1FA Antibody - #DF2526
| Product: | IL1FA Antibody |
| Catalog: | DF2526 |
| Description: | Rabbit polyclonal antibody to IL1FA |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Prediction: | Horse, Rabbit, Dog |
| Mol.Wt.: | 16kDa; 17kD(Calculated). |
| Uniprot: | Q8WWZ1 |
| RRID: | AB_2839732 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2526, RRID:AB_2839732.
Fold/Unfold
family of interleukin 1-theta; FIL1 theta; FIL1T; FKSG75; IL 38; IL-1 theta; IL-1F10 (canonical form IL-1F10a); IL-1F10; IL-1HY2; IL1 theta; IL1F10; IL1FA_HUMAN; IL1HY2; Interleukin 1 family member 10 (theta); Interleukin 1 receptor antagonist FKSG75; Interleukin 1 receptor antagonist homolog 2; Interleukin 1 receptor antagonist like FIL1 theta; Interleukin-1 family member 10; Interleukin-1 HY2; Interleukin-1 theta; interleukin-38;
Immunogens
Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.
- Q8WWZ1 IL1FA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCCAEKICILPNRGLARTKVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPGWFLCGPAEPQQPVQLTKESEPSARTKFYFEQSW
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8WWZ1 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y9 | Phosphorylation | Uniprot | |
| Y14 | Phosphorylation | Uniprot | |
| S105 | Phosphorylation | Uniprot | |
| S106 | Phosphorylation | Uniprot | |
| S108 | Phosphorylation | Uniprot |
Research Backgrounds
Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2.
Secreted.
Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil.
Belongs to the IL-1 family.
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