IL17RB Antibody - #DF2510
| Product: | IL17RB Antibody |
| Catalog: | DF2510 |
| Description: | Rabbit polyclonal antibody to IL17RB |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 49kDa,56kDa; 56kD(Calculated). |
| Uniprot: | Q9NRM6 |
| RRID: | AB_2839716 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2510, RRID:AB_2839716.
Fold/Unfold
CRL 4; CRL4; Cytokine receptor CRL4; EVI 27; EVI27; IL 17 receptor B; IL 17 receptor homolog 1; IL 17B receptor; IL 17RB; IL 17Rh1; IL17BR; IL17RB; IL17RH1; Interleukin 17 receptor B; Interleukin 17 receptor homolog 1; Interleukin 17 receptor homolog; Interleukin 17B receptor; MGC5245;
Immunogens
Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.
- Q9NRM6 I17RB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLVLLSLAALCRSAVPREPTVQCGSETGPSPEWMLQHDLIPGDLRDLRVEPVTTSVATGDYSILMNVSWVLRADASIRLLKATKICVTGKSNFQSYSCVRCNYTEAFQTQTRPSGGKWTFSYIGFPVELNTVYFIGAHNIPNANMNEDGPSMSVNFTSPGCLDHIMKYKKKCVKAGSLWDPNITACKKNEETVEVNFTTTPLGNRYMALIQHSTIIGFSQVFEPHQKKQTRASVVIPVTGDSEGATVQLTPYFPTCGSDCIRHKGTVVLCPQTGVPFPLDNNKSKPGGWLPLLLLSLLVATWVLVAGIYLMWRHERIKKTSFSTTTLLPPIKVLVVYPSEICFHHTICYFTEFLQNHCRSEVILEKWQKKKIAEMGPVQWLATQKKAADKVVFLLSNDVNSVCDGTCGKSEGSPSENSQDLFPLAFNLFCSDLRSQIHLHKYVVVYFREIDTKDDYNALSVCPKYHLMKDATAFCAELLHVKQQVSAGKRSQACHDGCCSL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NRM6 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S92 | Phosphorylation | Uniprot | |
| S96 | Phosphorylation | Uniprot | |
| Y97 | Phosphorylation | Uniprot | |
| S98 | Phosphorylation | Uniprot | |
| T321 | Phosphorylation | Uniprot | |
| S322 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.
Cell membrane>Single-pass type I membrane protein.
Secreted.
Expressed in several endocrine tissues, mostly in fetal and adult liver, kidney, pancreas, testis, colon, brain and small intestine; not detected in peripheral blood leukocytes, lymphoid organs, and most cell lines.
Interacts with DAZAP2.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
· Organismal Systems > Immune system > IL-17 signaling pathway. (View pathway)
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