HSPA4L Antibody - #DF2503

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Product: HSPA4L Antibody
Catalog: DF2503
Description: Rabbit polyclonal antibody to HSPA4L
Application: WB
Reactivity: Human, Mouse
Prediction: Bovine, Horse, Sheep, Rabbit, Dog
Mol.Wt.: 94 kDa; 95kD(Calculated).
Uniprot: O95757
RRID: AB_2839709

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 100ul $280 In stock
 200ul $350 In stock

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Prediction:
Bovine(92%), Horse(92%), Sheep(92%), Rabbit(100%), Dog(100%)
Clonality:
Polyclonal
Specificity:
HSPA4L Antibody detects endogenous levels of total HSPA4L.
RRID:
AB_2839709
Cite Format: Affinity Biosciences Cat# DF2503, RRID:AB_2839709.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

94kDa; AI461691; APG 1; Heat shock 70kDa protein 4 like; MGC117843; MGC187594; Osmotic stress protein 94; Osp94; OTTMUSP00000027739;

Immunogens

Immunogen:
Uniprot:

O95757(HS74L_HUMAN) >>Visit HPA database.

Gene(ID):
HSPA4L(22824)
Sequence:
MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNVRNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGMLLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALAYGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEALVDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSKMNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLKDISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVFCKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSKVKVKVRVNIHGIFSVASASVIEKQNLEGDHSDAPMETETSFKNENKDNMDKMQVDQEEGHQKCHAEHTPEEEIDHTGAKTKSAVSDKQDRLNQTLKKGKVKSIDLPIQSSLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKFITPEDLSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKALNDLGKKIQLVMKVIEAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQDPVVKVSEIVAKSKELDNFCNPIIYKPKPKAEVPEDKPKANSEHNGPMDGQSGTETKSDSTKDSSQHTKSSGEMEVD

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Dog
100
Horse
92
Bovine
92
Sheep
92
Chicken
75
Zebrafish
56
Pig
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95757 As Substrate

Site PTM Type Enzyme
S20 Phosphorylation
T25 Phosphorylation
R33 Methylation
K53 Ubiquitination
S54 Phosphorylation
K68 Ubiquitination
S74 Phosphorylation
R86 Methylation
K93 Ubiquitination
K102 Ubiquitination
K126 Ubiquitination
K194 Ubiquitination
K219 Acetylation
K221 Acetylation
K221 Ubiquitination
Y230 Phosphorylation
K249 Ubiquitination
K257 Ubiquitination
R265 Methylation
K272 Acetylation
K272 Ubiquitination
K274 Acetylation
K275 Ubiquitination
K351 Ubiquitination
K356 Ubiquitination
K360 Ubiquitination
T365 Phosphorylation
S384 Phosphorylation
K388 Methylation
K388 Ubiquitination
C417 S-Nitrosylation
C421 S-Nitrosylation
K422 Ubiquitination
K430 Ubiquitination
K437 Ubiquitination
K477 Ubiquitination
S508 Phosphorylation
T514 Phosphorylation
S517 Phosphorylation
C540 S-Nitrosylation
T545 Phosphorylation
T571 Phosphorylation
K573 Ubiquitination
S579 Phosphorylation
S587 Phosphorylation
C589 S-Nitrosylation
S599 Phosphorylation
Y600 Phosphorylation
K612 Ubiquitination
K621 Ubiquitination
Y627 Phosphorylation
K641 Ubiquitination
Y663 Phosphorylation
K671 Ubiquitination
Y684 Phosphorylation
Y692 Phosphorylation
Y726 Phosphorylation
K736 Ubiquitination
K739 Ubiquitination
K757 Ubiquitination
T761 Phosphorylation
K788 Ubiquitination
S814 Phosphorylation

Research Backgrounds

Function:

Possesses chaperone activity in vitro where it inhibits aggregation of citrate synthase.

Subcellular Location:

Cytoplasm. Nucleus.
Note: May translocate to the nucleus after heat shock.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Homodimer.

Family&Domains:

Belongs to the heat shock protein 70 family.

Research Fields

· Genetic Information Processing > Folding, sorting and degradation > Protein processing in endoplasmic reticulum.   (View pathway)

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