MRCKG Antibody - #DF2413
| Product: | MRCKG Antibody |
| Catalog: | DF2413 |
| Description: | Rabbit polyclonal antibody to MRCKG |
| Application: | WB IHC |
| Reactivity: | Human, Mouse |
| Prediction: | Sheep |
| Mol.Wt.: | 172kDa; 172kD(Calculated). |
| Uniprot: | Q6DT37 |
| RRID: | AB_2839619 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2413, RRID:AB_2839619.
Fold/Unfold
CDC42 binding protein kinase gamma; DMPK like gamma; DMPK2; MRCK gamma; Myotonic dystrophy kinase related CDC42 binding kinase gamma; Myotonic dystrophy protein kinase like alpha; Serine/threonine protein kinase MRCK gamma; CDC42 BPG;CDC42BPG
Immunogens
- Q6DT37 MRCKG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MERRLRALEQLARGEAGGCPGLDGLLDLLLALHHELSSGPLRRERSVAQFLSWASPFVSKVKELRLQRDDFEILKVIGRGAFGEVTVVRQRDTGQIFAMKMLHKWEMLKRAETACFREERDVLVKGDSRWVTTLHYAFQDEEYLYLVMDYYAGGDLLTLLSRFEDRLPPELAQFYLAEMVLAIHSLHQLGYVHRDVKPDNVLLDVNGHIRLADFGSCLRLNTNGMVDSSVAVGTPDYISPEILQAMEEGKGHYGPQCDWWSLGVCAYELLFGETPFYAESLVETYGKIMNHEDHLQFPPDVPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPMDTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQCLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGGEPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKPGSHTLRPRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSNDIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVLAAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSFSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLPLSPELESSP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6DT37 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S46 | Phosphorylation | Uniprot | |
| K75 | Ubiquitination | Uniprot | |
| K125 | Ubiquitination | Uniprot | |
| T222 | Phosphorylation | Uniprot | |
| T234 | Phosphorylation | Uniprot | |
| S239 | Phosphorylation | Uniprot | |
| S480 | Phosphorylation | Uniprot | |
| S646 | Phosphorylation | Uniprot | |
| K663 | Ubiquitination | Uniprot | |
| S740 | Phosphorylation | Uniprot | |
| S747 | Phosphorylation | Uniprot | |
| S817 | Phosphorylation | Uniprot | |
| S851 | Phosphorylation | Uniprot | |
| K875 | Ubiquitination | Uniprot | |
| S888 | Phosphorylation | Uniprot | |
| S1121 | Phosphorylation | Uniprot | |
| K1172 | Ubiquitination | Uniprot | |
| K1200 | Methylation | Uniprot | |
| K1385 | Ubiquitination | Uniprot | |
| S1462 | Phosphorylation | Uniprot | |
| R1473 | Methylation | Uniprot | |
| S1482 | Phosphorylation | Uniprot | |
| S1484 | Phosphorylation | Uniprot | |
| S1492 | Phosphorylation | Uniprot | |
| S1495 | Phosphorylation | Uniprot | |
| S1514 | Phosphorylation | Uniprot | |
| S1515 | Phosphorylation | Uniprot | |
| S1519 | Phosphorylation | Uniprot | |
| S1524 | Phosphorylation | Uniprot | |
| S1540 | Phosphorylation | Uniprot | |
| S1544 | Phosphorylation | Uniprot | |
| S1550 | Phosphorylation | Uniprot |
Research Backgrounds
May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation (By similarity).
Cytoplasm.
Note: Concentrates at the leading edge of cells.
Expressed in heart and skeletal muscle.
Homodimer and homotetramer via the coiled coil regions. Interacts tightly with GTP-bound but not GDP-bound CDC42 (By similarity).
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.