CD27 Antibody - #DF2296
| Product: | CD27 Antibody |
| Catalog: | DF2296 |
| Description: | Rabbit polyclonal antibody to CD27 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Rat |
| Prediction: | Bovine, Horse, Sheep |
| Mol.Wt.: | 29 kDa; 29kD(Calculated). |
| Uniprot: | P26842 |
| RRID: | AB_2839522 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF2296, RRID:AB_2839522.
Fold/Unfold
CD 27; Cd27; CD27 antigen; CD27 molecule; CD27_HUMAN; CD27L receptor; LPFS2; MGC20393; OTTHUMP00000238557; S152; T cell activation antigen CD27; T cell antivation antigen S152; T-cell activation antigen CD27; T14; TNFRSF 7; TNFRSF7; TNFSF7; Tp 55; Tp55; Tumor necrosis factor receptor superfamily member 7;
Immunogens
- P26842 CD27_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MARPHPWWLCVLGTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQRSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVEPAEPCHYSCPREEEGSTIPIQEDYRKPEPACSP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P26842 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S127 | O-Glycosylation | Uniprot | |
| T156 | Phosphorylation | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| K221 | Ubiquitination | Uniprot | |
| K253 | Ubiquitination | Uniprot |
Research Backgrounds
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.
Phosphorylated.
O-glycosylated with core 1 or possibly core 8 glycans.
Membrane>Single-pass type I membrane protein.
Found in most T-lymphocytes.
Homodimer. Interacts with SIVA1 and TRAF2.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction. (View pathway)
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