Product: SYF2 Antibody
Catalog: DF2224
Description: Rabbit polyclonal antibody to SYF2
Application: WB
Reactivity: Human, Mouse, Rat
Prediction: Pig, Zebrafish, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.: 28kDa; 29kD(Calculated).
Uniprot: O95926
RRID: AB_2839455

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 100ul $280 In stock
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Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Zebrafish(100%), Bovine(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%), Xenopus(100%)
Clonality:
Polyclonal
Specificity:
SYF2 Antibody detects endogenous levels of total SYF2.
RRID:
AB_2839455
Cite Format: Affinity Biosciences Cat# DF2224, RRID:AB_2839455.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

CBPIN; CCNDBP1 interactor; CCNDBP1-interactor; DKFZp564O2082; fSAP29; Functional spliceosome associated protein 29; GCIP interacting protein p29; GCIPIP; NTC31; P29; Pre mRNA splicing factor SYF2; Pre-mRNA-splicing factor syf2; syf2; SYF2 homolog; SYF2 homolog RNA splicing factor (S. cerevisiae); SYF2 homolog RNA splicing factor; SYF2_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
O95926 SYF2_HUMAN:

Abundantly expressed in the heart, skeletal muscle and kidney. Expressed at lower level other tissues.

Description:
May be involved in pre-mRNA splicing
Sequence:
MAAIAASEVLVDSAEEGSLAAAAELAAQKREQRLRKFRELHLMRNEARKLNHQEVVEEDKRLKLPANWEAKKARLEWELKEEEKKKECAARGEDYEKVKLLEISAEDAERWERKKKRKNPDLGFSDYAAAQLRQYHRLTKQIKPDMETYERLREKHGEEFFPTSNSLLHGTHVPSTEEIDRMVIDLEKQIEKRDKYSRRRPYNDDADIDYINERNAKFNKKAERFYGKYTAEIKQNLERGTAV

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Xenopus
100
Zebrafish
100
Chicken
100
Rabbit
100
Horse
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95926 As Substrate

Site PTM Type Enzyme
A2 Acetylation
S13 Phosphorylation
Y95 Phosphorylation
Y127 Phosphorylation
K143 Sumoylation
Y149 Phosphorylation
K155 Ubiquitination
Y196 Phosphorylation
Y210 Phosphorylation
Y226 Phosphorylation
K228 Acetylation
Y229 Phosphorylation
K234 Sumoylation
K234 Ubiquitination

Research Backgrounds

Function:

Involved in pre-mRNA splicing as component of the spliceosome.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Abundantly expressed in the heart, skeletal muscle and kidney. Expressed at lower level other tissues.

Subunit Structure:

Identified in the spliceosome C complex. Interacts with CCNDBP1.

Family&Domains:

Belongs to the SYF2 family.

Research Fields

· Genetic Information Processing > Transcription > Spliceosome.

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