RAMP2 Antibody - #DF7173

(1)   (2)  
Product: RAMP2 Antibody
Catalog: DF7173
Description: Rabbit polyclonal antibody to RAMP2
Application: WB IHC
Reactivity: Human, Mouse, Rat
Mol.Wt.: 20kD; 20kD(Calculated).
Uniprot: O60895
RRID: AB_2839125

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors
Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Clonality:
Polyclonal
Specificity:
RAMP2 Antibody detects endogenous levels of total RAMP2.
RRID:
AB_2839125
Cite Format: Affinity Biosciences Cat# DF7173, RRID:AB_2839125.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Calcitonin receptor like receptor activity modifying protein 2; Calcitonin-receptor-like receptor activity-modifying protein 2; CRLR activity modifying protein 2; CRLR activity-modifying protein 2; OTTMUSP00000002615; OTTMUSP00000037624; RAMP2; RAMP2_HUMAN; Receptor (calcitonin) activity modifying protein 2; Receptor activity modifying protein 2; Receptor activity modifying protein 2 isoform; Receptor activity-modifying protein 2; RP23-281C18.6;

Immunogens

Immunogen:
Uniprot:

O60895(RAMP2_HUMAN) >>Visit HPA database.

Gene(ID):
RAMP2(10266)
Expression:
O60895 RAMP2_HUMAN:

Strongly expressed in lung, breast, immune system and fetal tissues.

Sequence:
MASLRVERAGGPRLPRTRVGRPAALRLLLLLGAVLNPHEALAQPLPTTGTPGSEGGTVKNYETAVQFCWNHYKDQMDPIEKDWCDWAMISRPYSTLRDCLEHFAELFDLGFPNPLAERIIFETHQIHFANCSLVQPTFSDPPEDVLLAMIIAPICLIPFLITLVVWRSKDSEAQA

Research Backgrounds

Function:

Transports the calcitonin gene-related peptide type 1 receptor (CALCRL) to the plasma membrane. Acts as a receptor for adrenomedullin (AM) together with CALCRL.

Subcellular Location:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Strongly expressed in lung, breast, immune system and fetal tissues.

Subunit Structure:

Heterodimer of CALCRL and RAMP2.

Family&Domains:

Belongs to the RAMP family.

Research Fields

· Organismal Systems > Circulatory system > Vascular smooth muscle contraction.   (View pathway)

References

1). Adrenomedullin ameliorates palmitic acid-induced insulin resistance through PI3K/Akt pathway in adipocytes. ACTA DIABETOLOGICA, 2022 (PubMed: 34978596) [IF=3.8]

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.