MSR1 Antibody - #DF6694
Product: | MSR1 Antibody |
Catalog: | DF6694 |
Description: | Rabbit polyclonal antibody to MSR1 |
Application: | WB IHC IF/ICC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
Mol.Wt.: | 50kDa; 50kD(Calculated). |
Uniprot: | P21757 |
RRID: | AB_2838656 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF6694, RRID:AB_2838656.
Fold/Unfold
CD204; CD204 antigen; CD24; Macrophage acetylated LDL receptor I and II; Macrophage scavenger receptor 1; Macrophage scavenger receptor type III; Macrophage scavenger receptor types I and II; Msr 1; MSR1; MSRE_HUMAN; phSR1; phSR2; SCARA 1; SCARA1; Scavenger receptor class A member 1; Scavenger receptor class A, member 1; Scavenger receptor type A; Scvr; SR A; SRA;
Immunogens
Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain.
- P21757 MSRE_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEQWDHFHNQQEDTDSCSESVKFDARSMTALLPPNPKNSPSLQEKLKSFKAALIALYLLVFAVLIPLIGIVAAQLLKWETKNCSVSSTNANDITQSLTGKGNDSEEEMRFQEVFMEHMSNMEKRIQHILDMEANLMDTEHFQNFSMTTDQRFNDILLQLSTLFSSVQGHGNAIDEISKSLISLNTTLLDLQLNIENLNGKIQENTFKQQEEISKLEERVYNVSAEIMAMKEEQVHLEQEIKGEVKVLNNITNDLRLKDWEHSQTLRNITLIQGPPGPPGEKGDRGPTGESGPRGFPGPIGPPGLKGDRGAIGFPGSRGLPGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P21757 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T14 | Phosphorylation | Uniprot | |
S16 | Phosphorylation | Uniprot | |
S18 | Phosphorylation | Uniprot | |
S27 | Phosphorylation | Uniprot | |
T29 | Phosphorylation | Uniprot | |
N221 | N-Glycosylation | Uniprot | |
K245 | Methylation | Uniprot | |
T251 | Phosphorylation | Uniprot |
Research Backgrounds
Membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low density lipoproteins (LDL). Isoform III does not internalize acetylated LDL.
Membrane>Single-pass type II membrane protein.
Isoform I, isoform II and isoform III are expressed in monocyte-derived macrophages. Isoform I and isoform II are expressed in the liver, placenta and brain.
Homotrimer (By similarity). Interacts with MYO18A.
Research Fields
· Cellular Processes > Transport and catabolism > Phagosome. (View pathway)
References
Application: IF/ICC Species: mouse Sample: Raw264.7 cells
Application: WB Species: Mice Sample: RAW264.7 cells
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