C19orf10 Antibody - #DF6236
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF6236, RRID:AB_2838202.
Fold/Unfold
C19orf10; Chromosome 19 open reading frame 10; CS010_HUMAN; EUROIMAGE1875335; IL 25; IL 27; IL-25; IL25; IL27; IL27w; Interleukin 25; Interleukin 27 working designation; Interleukin-25; Interleukin25; R33729 1; R337291; SF20; Stromal cell derived growth factor; Stromal cell derived growth factor SF20; Stromal cell-derived growth factor SF20; Uncharacterized protein C19orf10 precursor; UPF0556 protein C19orf10;
Immunogens
Expressed in eosinophils (at protein level) (PubMed:29954947). Expressed in bone marrow cells (PubMed:25581518). Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties (PubMed:17362502).
- Q969H8 MYDGF_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAPSGGWNGVGASLWAALLLGAVALRPAEAVSEPTTVAFDVRPGGVVHSFSHNVGPGDKYTCMFTYASQGGTNEQWQMSLGTSEDHQHFTCTIWRPQGKSYLYFTQFKAEVRGAEIEYAMAYSKAAFERESDVPLKTEEFEVTKTAVAHRPGAFKAELSKLVIVAKASRTEL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q969H8 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S33 | Phosphorylation | Uniprot | |
| T36 | Phosphorylation | Uniprot | |
| Y61 | Phosphorylation | Uniprot | |
| Y67 | Phosphorylation | Uniprot | |
| S84 | Phosphorylation | Uniprot | |
| Y102 | Phosphorylation | Uniprot | |
| Y104 | Phosphorylation | Uniprot | |
| R113 | Methylation | Uniprot | |
| Y119 | Phosphorylation | Uniprot | |
| S132 | Phosphorylation | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| T138 | Phosphorylation | Uniprot | |
| T146 | Phosphorylation | Uniprot | |
| S169 | Phosphorylation | Uniprot |
Research Backgrounds
Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway (By similarity). Involved in endothelial cell proliferation and angiogenesis.
Secreted. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.
Note: The C-terminal RTEL motif may provide retention in the endoplasmic reticulum.
Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.
Belongs to the MYDGF family.
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