GPR91 Antibody - #AF5316

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Product: GPR91 Antibody
Catalog: AF5316
Description: Rabbit polyclonal antibody to GPR91
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit
Mol.Wt.: 38 kDa; 39kD(Calculated).
Uniprot: Q9BXA5
RRID: AB_2837801

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(89%), Bovine(100%), Horse(89%), Sheep(100%), Rabbit(100%)
Clonality:
Polyclonal
Specificity:
GPR91 Antibody detects endogenous levels of total GPR91.
RRID:
AB_2837801
Cite Format: Affinity Biosciences Cat# AF5316, RRID:AB_2837801.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

G protein coupled receptor 91; G-protein coupled receptor 91; GPR 91; P2Y purinoceptor 1; P2Y purinoceptor 1 like; P2Y purinoceptor 1-like; Purinergic Receptor P2U2; Succinate receptor 1; Succinate receptor; SUCN R1; SUCNR 1; SUCNR1; SUCR1_HUMAN;

Immunogens

Immunogen:
Uniprot:

Q9BXA5(SUCR1_HUMAN) >>Visit HPA database.

Gene(ID):
SUCNR1(56670)
Expression:
Q9BXA5 SUCR1_HUMAN:

Expressed specifically in kidney.

Description:
FunctionReceptor for succinate.Tissue specificityExpressed specifically in kidney.Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Sequence:
MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSSNIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYTSILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPILPLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYYKIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIASRLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMNQLRHNFKSLTSFSRWAHELLLSFREK

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Rabbit
100
Pig
89
Horse
89
Dog
78
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

Research Backgrounds

Function:

Receptor for succinate.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed specifically in kidney.

Family&Domains:

Belongs to the G-protein coupled receptor 1 family.

Research Fields

· Environmental Information Processing > Signal transduction > cAMP signaling pathway.   (View pathway)

References

1). Succinate level is increased and succinate dehydrogenase exerts forward and reverse catalytic activities in lipopolysaccharides-stimulated cardiac tissue: The protective role of dimethyl malonate. European Journal of Pharmacology, 2023 (PubMed: 36549501) [IF=5.0]

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