Claudin 5 Antibody - #AF5216
|Product:||Claudin 5 Antibody|
|Application:||WB, IHC, IF/ICC|
|Reactivity:||Human, Mouse, Rat, Pig, Bovine, Monkey|
|Prediction:||Pig, Bovine, Rabbit, Chicken, Xenopus|
|Mol.Wt.:||23 kDa; 23kD(Calculated).|
*The optimal dilutions should be determined by the end user.
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# AF5216, RRID:AB_2837702.
Androgen withdrawal and apoptosis induced protein RVP1 like; AWAL; BEC 1; BEC1; Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome); Claudin-5; Claudin5; CLD5_HUMAN; CLDN 5; Cldn5; CPETR L1; CPETRL 1; CPETRL1; TMDVCF; TMVCF; Transmembrane protein deleted in VCFS; Transmembrane protein deleted in velocardiofacial syndrome;
- O00501 CLD5_HUMAN:
- Protein BLAST With
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O00501 As Substrate
Plays a major role in tight junction-specific obliteration of the intercellular space.
Cell junction>Tight junction. Cell membrane>Multi-pass membrane protein.
Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ (By similarity).
Belongs to the claudin family.
· Cellular Processes > Cellular community - eukaryotes > Tight junction. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Cell adhesion molecules (CAMs). (View pathway)
· Human Diseases > Infectious diseases: Viral > Hepatitis C.
· Organismal Systems > Immune system > Leukocyte transendothelial migration. (View pathway)
Application: WB Species: Human Sample: HMVEC cells
Application: WB Species: Mice Sample:
Application: WB Species: Rat Sample: Cerebrum
Application: WB Species: rat Sample:
Application: WB Species: human Sample: HUVECs
Application: WB Species: Rat Sample: cerebral cortex vascular tissues
Application: WB Species: Rat Sample: brain tissues
Application: WB Species: rat Sample: brain
Application: WB Species: Human Sample: hBMECs
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