TAS2R49 Antibody - #DF5163

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Product: TAS2R49 Antibody
Catalog: DF5163
Description: Rabbit polyclonal antibody to TAS2R49
Application: WB IHC IF/ICC
Reactivity: Human
Mol.Wt.: 38 KD; 35kD(Calculated).
Uniprot: P59543
RRID: AB_2837512

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
TAS2R49 Antibody detects endogenous levels of total TAS2R49.
RRID:
AB_2837512
Cite Format: Affinity Biosciences Cat# DF5163, RRID:AB_2837512.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

T2R20; T2R20_HUMAN; T2R49; T2R56; TAS2R20; TAS2R49; Taste receptor type 2 member 20; Taste receptor type 2 member 49; Taste receptor type 2 member 56;

Immunogens

Immunogen:
Uniprot:

P59543(T2R20_HUMAN) >>Visit HPA database.

Gene(ID):
TAS2R20(259295)
Expression:
P59543 T2R20_HUMAN:

Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Sequence:
MMSFLHIVFSILVVVAFILGNFANGFIALINFIAWVKRQKISSADQIIAALAVSRVGLLWVILLHWYSTVLNPTSSNLKVIIFISNAWAVTNHFSIWLATSLSIFYLLKIVNFSRLIFHHLKRKAKSVVLVIVLGSLFFLVCHLVMKHTYINVWTEECEGNVTWKIKLRNAMHLSNLTVAMLANLIPFTLTLISFLLLIYSLCKHLKKMQLHGKGSQDPSTKIHIKALQTVTSFLILLAIYFLCLIISFWNFKMRPKEIVLMLCQAFGIIYPSFHSFILIWGNKTLKQTFLSVLWQVTCWAKGQNQSTP

PTMs - P59543 As Substrate

Site PTM Type Enzyme
S216 Phosphorylation

Research Backgrounds

Function:

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).

Subcellular Location:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

Family&Domains:

Belongs to the G-protein coupled receptor T2R family.

Research Fields

· Organismal Systems > Sensory system > Taste transduction.

Restrictive clause

 

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For Research Use Only.
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