Product: OR1D2 Antibody
Catalog: DF5061
Description: Rabbit polyclonal antibody to OR1D2
Application: WB IF/ICC
Reactivity: Human
Mol.Wt.: 40 KD; 35kD(Calculated).
Uniprot: P34982
RRID: AB_2837420

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
OR1D2 Antibody detects endogenous levels of total OR1D2.
RRID:
AB_2837420
Cite Format: Affinity Biosciences Cat# DF5061, RRID:AB_2837420.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Olfactory receptor 17-4; Olfactory receptor 1D2; Olfactory receptor like protein HGMP07E; Olfactory receptor OR17-6; Olfactory receptor, family 1, subfamily D, member 2; Olfactory receptor-like protein HGMP07E; OLFR1; OR17-4; OR1D2; OR1D2_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P34982 OR1D2_HUMAN:

Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium.

Sequence:
MDGGNQSEGSEFLLLGMSESPEQQRILFWMFLSMYLVTVVGNVLIILAISSDSRLHTPVYFFLANLSFTDLFFVTNTIPKMLVNLQSHNKAISYAGCLTQLYFLVSLVALDNLILAVMAYDRYVAICCPLHYTTAMSPKLCILLLSLCWVLSVLYGLIHTLLMTRVTFCGSRKIHYIFCEMYVLLRMACSNIQINHTVLIATGCFIFLIPFGFVIISYVLIIRAILRIPSVSKKYKAFSTCASHLGAVSLFYGTLCMVYLKPLHTYSVKDSVATVMYAVVTPMMNPFIYSLRNKDMHGALGRLLDKHFKRLT

PTMs - P34982 As Substrate

Site PTM Type Enzyme
Y123 Phosphorylation
Y218 Phosphorylation

Research Backgrounds

Function:

Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.
Note: In spermatazoa is localized in the midpiece and is translocated to the head region upon receptor stimulation with bourgeonal.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in testis. Expressed in spermatozoa (at protein level). Expressed in olfactory epithelium.

Family&Domains:

Belongs to the G-protein coupled receptor 1 family.

Research Fields

· Organismal Systems > Sensory system > Olfactory transduction.

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