OR10A6 Antibody - #DF5047

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Product: OR10A6 Antibody
Catalog: DF5047
Description: Rabbit polyclonal antibody to OR10A6
Application: WB IF/ICC
Reactivity: Human
Prediction: Dog
Mol.Wt.: 35 KD; 35kD(Calculated).
Uniprot: Q8NH74
RRID: AB_2837406

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Prediction:
Dog(89%)
Clonality:
Polyclonal
Specificity:
OR10A6 Antibody detects endogenous levels of total OR10A6.
RRID:
AB_2837406
Cite Format: Affinity Biosciences Cat# DF5047, RRID:AB_2837406.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

O10A6_HUMAN; Olfactory receptor family 10 subfamily A member 6; Olfactory receptor 10A6; Olfactory receptor OR11-96; OR10A6; OR11 96;

Immunogens

Immunogen:
Uniprot:

Q8NH74(O10A6_HUMAN) >>Visit HPA database.

Gene(ID):
OR10A6(390093)
Sequence:
MERQNQSCVVEFILLGFSNYPELQGQLFVAFLVIYLVTLIGNAIIIVIVSLDQSLHVPMYLFLLNLSVVDLSFSAVIMPEMLVVLSTEKTTISFGGCFAQMYFILLFGGAECFLLGAMAYDRFAAICHPLNYQMIMNKGVFMKLIIFSWALGFMLGTVQTSWVSSFPFCGLNEINHISCETPAVLELACADTFLFEIYAFTGTFLIILVPFLLILLSYIRVLFAILKMPSTTGRQKAFSTCAAHLTSVTLFYGTASMTYLQPKSGYSPETKKVMSLSYSLLTPLLNLLIYSLRNSEMKRALMKLWRRRVVLHTI

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
89
Bovine
78
Pig
0
Horse
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

Research Backgrounds

Function:

Odorant receptor.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Family&Domains:

Belongs to the G-protein coupled receptor 1 family.

Research Fields

· Organismal Systems > Sensory system > Olfactory transduction.

References

1). Distinct sets of olfactory receptors highly expressed in different human tissues evaluated by meta-transcriptome analysis: Association of OR10A6 in skin with keratinization. Frontiers in Cell and Developmental Biology, 2023 (PubMed: 36776557) [IF=5.5]

Application: IF/ICC    Species: Human    Sample: skin

FIGURE 3 Expression of ORs in human keratinocytes and skin. (A) RT-PCR analysis of OR5P2, OR5P3, and OR10A6. GAPDH was used for RNA quality control. M: Marker. (B) Immunofluorescence staining of OR10A6 (green) in human keratinocytes and skin. Cell nuclei appear in blue or white. Magnified sections are indicated by white dashed squares. Bar = 50 μm. (C–F) Immunofluorescence staining of OR10A6 (green) and KRT14, Melan A, Ki-67 or MCSP (red) in human skin. Cell nuclei appear in white. Magnified sections are shown in white dashed squares. Bar = 20 μm. (G) Ratio of OR10A6-positive cells, OR10A6 + Ki-67-positive cells and OR10A6 + MCSP-positive cells counted in skin sections.

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