RXFP3 Antibody - #DF5149
| Product: | RXFP3 Antibody |
| Catalog: | DF5149 |
| Description: | Rabbit polyclonal antibody to RXFP3 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Bovine, Sheep, Rabbit |
| Mol.Wt.: | 51 KD; 51kD(Calculated). |
| Uniprot: | Q9NSD7 |
| RRID: | AB_2837339 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF5149, RRID:AB_2837339.
Fold/Unfold
G protein coupled receptor GPCR135; G protein coupled receptor SALPR; G protein-coupled receptor SALPR; G-protein coupled receptor GPCR135; GPCR 135; GPCR135; Gprotein coupled receptor SALPR; Relaxin 3 receptor 1; Relaxin 3 receptor1; Relaxin 3/INSL7 receptor 1; Relaxin 3/INSL7 receptor1; Relaxin family peptide receptor 3; Relaxin family peptide receptor3; Relaxin-3 receptor 1; Relaxin/insulin like family peptide receptor 3; Relaxin3 receptor 1; Relaxin3 receptor1; RL3 R1; RL3R 1; RL3R1; RL3R1_HUMAN; RLN3 receptor 1; RLN3 receptor1; RLN3R1; RXFP3; RXFPR3; SALP R; SALPR; somatostatin and angiotensin like peptide receptor; Somatostatin- and angiotensin-like peptide receptor;
Immunogens
Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
- Q9NSD7 RL3R1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQMADAATIATMNKAAGGDKLAELFSLVPDLLEAANTSGNASLQLPDLWWELGLELPDGAPPGHPPGSGGAESADTEARVRILISVVYWVVCALGLAGNLLVLYLMKSMQGWRKSSINLFVTNLALTDFQFVLTLPFWAVENALDFKWPFGKAMCKIVSMVTSMNMYASVFFLTAMSVTRYHSVASALKSHRTRGHGRGDCCGRSLGDSCCFSAKALCVWIWALAALASLPSAIFSTTVKVMGEELCLVRFPDKLLGRDRQFWLGLYHSQKVLLGFVLPLGIIILCYLLLVRFIADRRAAGTKGGAAVAGGRPTGASARRLSKVTKSVTIVVLSFFLCWLPNQALTTWSILIKFNAVPFSQEYFLCQVYAFPVSVCLAHSNSCLNPVLYCLVRREFRKALKSLLWRIASPSITSMRPFTATTKPEHEDQGLQAPAPPHAAAEPDLLYYPPGVVVYSGGRYDLLPSSSAY
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9NSD7 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S269 | Phosphorylation | Uniprot | |
| R312 | Methylation | Uniprot | |
| R320 | Methylation | Uniprot | |
| Y460 | Phosphorylation | Uniprot | |
| Y469 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Cell membrane>Multi-pass membrane protein.
Expressed predominantly in brain regions. Highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, quite low level in cerebellum. In peripheral tissues, relatively high levels in adrenal glands, low levels in pancreas, salivary gland, placenta, mammary gland and testis.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Organismal Systems > Endocrine system > Relaxin signaling pathway.
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