MC5R Antibody - #DF4985
| Product: | MC5R Antibody |
| Catalog: | DF4985 |
| Description: | Rabbit polyclonal antibody to MC5R |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 40 KD; 37kD(Calculated). |
| Uniprot: | P33032 |
| RRID: | AB_2837334 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4985, RRID:AB_2837334.
Fold/Unfold
MC-2; MC2; MC5 R; MC5-R; MC5R; MC5R_HUMAN; Melanocortin 5 receptor; Melanocortin receptor 5;
Immunogens
- P33032 MC5R_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P33032 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T143 | Phosphorylation | Uniprot | |
| Y150 | Phosphorylation | Uniprot | |
| T155 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
Cell membrane>Multi-pass membrane protein.
Expressed in the brain but not in the melanoma cells.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
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