EDG7 Antibody - #DF4922
| Product: | EDG7 Antibody |
| Catalog: | DF4922 |
| Description: | Rabbit polyclonal antibody to EDG7 |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| Mol.Wt.: | 47 KD; 40kD(Calculated). |
| Uniprot: | Q9UBY5 |
| RRID: | AB_2837275 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4922, RRID:AB_2837275.
Fold/Unfold
Calcium mobilizing lysophosphatidic acid receptor LP A3; Calcium mobilizing lysophosphatidic acid receptor LPA 3; Calcium mobilizing lysophosphatidic acid receptor LPA3; EDG 7; Endothelial cell differentiation gene 7; Endothelial differentiation lysophosphatidic acid G protein coupled receptor 7; FLJ98231; GPCR; HOFNH 30; HOFNH30; LP A3; LPA 3; LPA receptor 3; LPA receptor EDG 7; LPA receptor EDG7; LPA-3; LPA3; LPAR 3; Lpar3; LPAR3_HUMAN; Lysophosphatidic acid receptor 3; Lysophosphatidic acid receptor Edg 7; Lysophosphatidic acid receptor Edg-7; Lysophosphatidic acid receptor Edg7; OTTHUMP00000011573; RP4 678I3; RP4678I3;
Immunogens
Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.
- Q9UBY5 LPAR3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UBY5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T118 | Phosphorylation | Uniprot | |
| Y206 | Phosphorylation | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| Y293 | Phosphorylation | Uniprot | |
| Y301 | Phosphorylation | Uniprot | |
| S321 | Phosphorylation | Uniprot | |
| S325 | Phosphorylation | Uniprot | |
| S329 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.
Cell membrane>Multi-pass membrane protein.
Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signal transduction > Rap1 signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > Phospholipase D signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway. (View pathway)
· Human Diseases > Cancers: Overview > Pathways in cancer. (View pathway)
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