GPR119 Antibody - #DF4892
| Product: | GPR119 Antibody |
| Catalog: | DF4892 |
| Description: | Rabbit polyclonal antibody to GPR119 |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse |
| Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| Mol.Wt.: | 37 KD; 37kD(Calculated). |
| Uniprot: | Q8TDV5 |
| RRID: | AB_2837245 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4892, RRID:AB_2837245.
Fold/Unfold
G protein coupled receptor 119; G protein coupled receptor 2; G-protein coupled receptor 119; Glucose dependent insulinotropic receptor; Glucose-dependent insulinotropic receptor; GP119_HUMAN; GPCR 2; GPCR2; GPR 119; Gpr119; HGPCR 2; HGPCR2; MGC119957; Seven transmembrane helix receptor;
Immunogens
- Q8TDV5 GP119_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MESSFSFGVILAVLASLIIATNTLVAVAVLLLIHKNDGVSLCFTLNLAVADTLIGVAISGLLTDQLSSPSRPTQKTLCSLRMAFVTSSAAASVLTVMLITFDRYLAIKQPFRYLKIMSGFVAGACIAGLWLVSYLIGFLPLGIPMFQQTAYKGQCSFFAVFHPHFVLTLSCVGFFPAMLLFVFFYCDMLKIASMHSQQIRKMEHAGAMAGGYRSPRTPSDFKALRTVSVLIGSFALSWTPFLITGIVQVACQECHLYLVLERYLWLLGVGNSLLNPLIYAYWQKEVRLQLYHMALGVKKVLTSFLLFLSARNCGPERPRESSCHIVTISSSEFDG
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8TDV5 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K201 | Ubiquitination | Uniprot | |
| T302 | Phosphorylation | Uniprot | |
| S303 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway.
Cell membrane>Multi-pass membrane protein.
Predominantly expressed in the pancreas, especially in the islets.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signal transduction > cAMP signaling pathway. (View pathway)
· Organismal Systems > Endocrine system > Insulin secretion. (View pathway)
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