EDG5 Antibody - #DF4871
| Product: | EDG5 Antibody |
| Catalog: | DF4871 |
| Description: | Rabbit polyclonal antibody to EDG5 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Horse, Sheep |
| Mol.Wt.: | 39 KD; 39kD(Calculated). |
| Uniprot: | O95136 |
| RRID: | AB_2837234 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4871, RRID:AB_2837234.
Fold/Unfold
AGR16; EDG 5; EDG5; Endothelial Cell Differentiation Gene 5; Endothelial differentiation G protein coupled receptor 5; Endothelial differentiation G-protein coupled receptor 5; Endothelial differentiation sphingolipid G protein coupled receptor 5; Gpcr13; H218; LPb2; Lysophospholipid receptor B2; S1P receptor 2; S1P receptor Edg 5; S1P receptor Edg-5; S1P receptor EDG5; S1P2; S1pr2; S1PR2_HUMAN; Sphingosine 1 phosphate receptor Edg 5; Sphingosine 1-phosphate receptor 2; Sphingosine 1-phosphate receptor Edg-5;
Immunogens
- O95136 S1PR2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSLYSEYLNPNKVQEHYNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAASDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQCWRPGVGVQGRRRGGTPGHHLLPLRSSSSLERGMHMPTSPTFLEGNTVV
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O95136 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S142 | Phosphorylation | Uniprot | |
| K144 | Acetylation | Uniprot | |
| S333 | Phosphorylation | Uniprot | |
| S343 | Phosphorylation | Uniprot |
Research Backgrounds
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Receptor for the chemokine-like protein FAM19A5. Mediates the inhibitory effect of FAM19A5 on vascular smooth muscle cell proliferation and migration (By similarity).
Cell membrane>Multi-pass membrane protein.
Belongs to the G-protein coupled receptor 1 family.
Research Fields
· Environmental Information Processing > Signal transduction > Sphingolipid signaling pathway. (View pathway)
· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.
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