Product: ADORA3 Antibody
Catalog: DF4851
Description: Rabbit polyclonal antibody to ADORA3
Application: WB IHC IF/ICC
Reactivity: Human, Mouse
Mol.Wt.: 38 KD; 36kD(Calculated).
Uniprot: P0DMS8
RRID: AB_2837215

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse
Clonality:
Polyclonal
Specificity:
ADORA3 Antibody detects endogenous levels of total ADORA3.
RRID:
AB_2837215
Cite Format: Affinity Biosciences Cat# DF4851, RRID:AB_2837215.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

A3AR; A3R; AA3R; AA3R_HUMAN; AD 026; AD026; Adenosine A3 receptor; Adenosine receptor A3; ADORA 3; ADORA3; ARA3; bA552M11.5; Gpcr2; RP11 552M11.7; TGPCR1;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
P0DMS8 AA3R_HUMAN:

Expressed in the lung and bone. Expressed at lower levels in osteosarcoma tissues (at protein level).

Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE

PTMs - P0DMS8 As Substrate

Site PTM Type Enzyme
S213 Phosphorylation

Research Backgrounds

Function:

Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.

Subcellular Location:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Expressed in the lung and bone. Expressed at lower levels in osteosarcoma tissues (at protein level).

Family&Domains:

Belongs to the G-protein coupled receptor 1 family.

Research Fields

· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Sphingolipid signaling pathway.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

Restrictive clause

 

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For Research Use Only.
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