FST Antibody - #DF4839
Product: | FST Antibody |
Catalog: | DF4839 |
Description: | Rabbit polyclonal antibody to FST |
Application: | WB IF/ICC |
Reactivity: | Human, Mouse, Rat |
Prediction: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
Mol.Wt.: | 65 KD; 38kD(Calculated). |
Uniprot: | P19883 |
RRID: | AB_2837204 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4839, RRID:AB_2837204.
Fold/Unfold
Activin binding protein; Activin-binding protein; Follistatin; FS; fst; FST_HUMAN; Human follistatin gene;
Immunogens
Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.
- P19883 FST_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MVRARHQPGGLCLLLLLLCQFMEDRSAQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDELCPDSKSDEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQDYSFPISSILEW
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P19883 As Substrate
Site | PTM Type | Enzyme | Source |
---|---|---|---|
S230 | Phosphorylation | Uniprot | |
S277 | Phosphorylation | Uniprot |
Research Backgrounds
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
Secreted.
Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.
Monomer. Isoform 2/FS-288 interacts with GDF11.
Research Fields
· Environmental Information Processing > Signal transduction > TGF-beta signaling pathway. (View pathway)
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