TBX3 Antibody - #DF4770
| Product: | TBX3 Antibody |
| Catalog: | DF4770 |
| Description: | Rabbit polyclonal antibody to TBX3 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog, Xenopus |
| Mol.Wt.: | 79 KD; 79kD(Calculated). |
| Uniprot: | O15119 |
| RRID: | AB_2837124 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4770, RRID:AB_2837124.
Fold/Unfold
Bladder cancer related protein XHL; T box 2; T box 3; T box protein 2; T box protein 3; T box transcription factor TBX2; T box transcription factor TBX3; TBX3-ISO; UMS; XHL;
Immunogens
- O15119 TBX3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTVGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFAPLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSELQSIQRLVSGLEAKPDRSRSASP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15119 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K104 | Ubiquitination | Uniprot | |
| K110 | Ubiquitination | Uniprot | |
| K118 | Ubiquitination | Uniprot | |
| T121 | Phosphorylation | Uniprot | |
| K127 | Ubiquitination | Uniprot | |
| Y163 | Phosphorylation | Uniprot | |
| Y185 | Phosphorylation | Uniprot | |
| S190 | Phosphorylation | Uniprot | |
| T203 | Phosphorylation | Uniprot | |
| K206 | Ubiquitination | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| Y265 | Phosphorylation | Uniprot | |
| K293 | Ubiquitination | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| K313 | Ubiquitination | Uniprot | |
| S371 | Phosphorylation | Uniprot | |
| S375 | Phosphorylation | Uniprot | |
| S381 | Phosphorylation | Uniprot | |
| S396 | Phosphorylation | Uniprot | |
| S400 | Phosphorylation | Uniprot | |
| S409 | Phosphorylation | Uniprot | |
| K413 | Ubiquitination | Uniprot | |
| S432 | Phosphorylation | Uniprot | |
| S435 | Phosphorylation | Uniprot | |
| S438 | Phosphorylation | Uniprot | |
| T441 | Phosphorylation | Uniprot | |
| S443 | Phosphorylation | Uniprot | |
| S444 | Phosphorylation | Uniprot | |
| S445 | Phosphorylation | Uniprot | |
| T446 | Phosphorylation | Uniprot | |
| S456 | Phosphorylation | Uniprot | |
| T462 | Phosphorylation | Uniprot | |
| K466 | Ubiquitination | Uniprot | |
| S680 | Phosphorylation | Uniprot | |
| S707 | Phosphorylation | Uniprot | |
| K714 | Ubiquitination | Uniprot | |
| T718 | Phosphorylation | Uniprot | |
| S719 | Phosphorylation | Q9Y243 (AKT3) | Uniprot |
| S729 | Phosphorylation | Uniprot | |
| K734 | Ubiquitination | Uniprot | |
| S738 | Phosphorylation | Uniprot | |
| S740 | Phosphorylation | Uniprot | |
| S742 | Phosphorylation | Uniprot |
Research Backgrounds
Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence.
Nucleus.
Widely expressed.
Interacts with PML (isoform PML-4).
Research Fields
· Cellular Processes > Cellular community - eukaryotes > Signaling pathways regulating pluripotency of stem cells. (View pathway)
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