TBXAS1 Antibody | Affinity Biosciences

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Western blot analysis of extracts from Jurkat cells, using THAS antibody.

Product:	TBXAS1 Antibody
Catalog:	DF4746
Description:	Rabbit polyclonal antibody to TBXAS1
Application:	WB IF/ICC
Reactivity:	Human
Prediction:	Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Mol.Wt.:	61kD; 61kD(Calculated).
Uniprot:	P24557
RRID:	AB_2837097

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

Lead Time: Same day delivery

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Related Downloads

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human

Prediction:

Pig(88%), Bovine(88%), Horse(88%), Sheep(88%), Rabbit(100%), Dog(100%), Chicken(88%), Xenopus(88%)

Clonality:

Polyclonal

Specificity:

TBXAS1 Antibody detects endogenous levels of total TBXAS1.

RRID:

AB_2837097
Cite Format: Affinity Biosciences Cat# DF4746, RRID:AB_2837097.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

BDPLT14; CYP5; CYP5A1; Cytochrome P450 5A1; Cytochrome P450, family 5, subfamily A, polypeptide 1; FLJ52771; GHOSAL; Platelet cytochrome P450 subfamily V; Tbxas1; THAS; THAS_HUMAN; Thromboxane A synthase 1 (platelet); Thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A); Thromboxane A synthase 1; Thromboxane A synthase 1 platelet cytochrome P450 subfamily V; Thromboxane-A synthase; TS; TXA synthase; TXAS; TXS;

Immunogens

Immunogen:

Uniprot:

P24557(THAS_HUMAN) >>Visit HPA database.

Gene(ID):

TBXAS1(6916)

Expression:

P24557 THAS_HUMAN:

Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.

Sequence:

P24557 THAS_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MEALGFLKLEVNGPMVTVALSVALLALLKWYSTSAFSRLEKLGLRHPKPSPFIGNLTFFRQGFWESQMELRKLYGPLCGYYLGRRMFIVISEPDMIKQVLVENFSNFTNRMASGLEFKSVADSVLFLRDKRWEEVRGALMSAFSPEKLNEMVPLISQACDLLLAHLKRYAESGDAFDIQRCYCNYTTDVVASVAFGTPVDSWQAPEDPFVKHCKRFFEFCIPRPILVLLLSFPSIMVPLARILPNKNRDELNGFFNKLIRNVIALRDQQAAEERRRDFLQMVLDARHSASPMGVQDFDIVRDVFSSTGCKPNPSRQHQPSPMARPLTVDEIVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGLPYLDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPLQLESKSALGPKNGVYIKIVSR

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Rabbit

100

Dog

100

Pig

Horse

Bovine

Sheep

Xenopus

Chicken

Zebrafish

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P24557 As Substrate

P24557

Site	PTM Type	Enzyme	Source
T57	Phosphorylation		Uniprot

Research Backgrounds

P24557_THAS_HUMAN

Subcellular Location:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Tissue Specificity:

Platelets, lung, kidney, spleen, macrophages and lung fibroblasts.

Subunit Structure:

Monomer.

Family&Domains:

Belongs to the cytochrome P450 family.

Research Fields

· Metabolism > Lipid metabolism > Arachidonic acid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Immune system > Platelet activation. (View pathway)

Restrictive clause

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For Research Use Only.
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TBXAS1 Antibody - #DF4746