Cytochrome P450 26C1 Antibody - #DF4743
| Product: | Cytochrome P450 26C1 Antibody |
| Catalog: | DF4743 |
| Description: | Rabbit polyclonal antibody to Cytochrome P450 26C1 |
| Application: | WB |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Rabbit |
| Mol.Wt.: | 57 KD; 57kD(Calculated). |
| Uniprot: | Q6V0L0 |
| RRID: | AB_2837094 |
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4743, RRID:AB_2837094.
Fold/Unfold
CP26C_HUMAN; cyp26b1l; CYP26C1; cyp26d1; Cytochrome P450 26C1; Cytochrome P450 family 26 subfamily C polypeptide 1; Cytochrome P450, subfamily XXVIC polypeptide 1; EG546726; FFDD4; FLJ45301; MGC158120; retinoic acid catabolizing enzyme;
Immunogens
- Q6V0L0 CP26C_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFPWGLSCLSVLGAAGTALLCAGLLLSLAQHLWTLRWMLSRDRASTLPLPKGSMGWPFFGETLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQWPQSAHILLGSHTLLGAVGEPHRRRRKVLARVFSRAALERYVPRLQGALRHEVRSWCAAGGPVSVYDASKALTFRMAARILLGLRLDEAQCATLARTFEQLVENLFSLPLDVPFSGLRKGIRARDQLHRHLEGAISEKLHEDKAAEPGDALDLIIHSARELGHEPSMQELKESAVELLFAAFFTTASASTSLVLLLLQHPAAIAKIREELVAQGLGRACGCAPGAAGGSEGPPPDCGCEPDLSLAALGRLRYVDCVVKEVLRLLPPVSGGYRTALRTFELDGYQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGAAREDSRGASSRFHYIPFGGGARSCLGQELAQAVLQLLAVELVRTARWELATPAFPAMQTVPIVHPVDGLRLFFHPLTPSVAGNGLCL
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q6V0L0 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y80 | Phosphorylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| T300 | Phosphorylation | Uniprot | |
| K321 | Ubiquitination | Uniprot |
Research Backgrounds
Plays a role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA (preferred substrate).
Membrane>Single-pass membrane protein.
Detected in most tissues at very low level.
Belongs to the cytochrome P450 family.
Research Fields
· Metabolism > Metabolism of cofactors and vitamins > Retinol metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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