MYL6 Antibody - #DF4718

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Product: MYL6 Antibody
Catalog: DF4718
Description: Rabbit polyclonal antibody to MYL6
Application: WB IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Pig, Bovine, Horse, Sheep, Rabbit
Mol.Wt.: 17 KD; 17kD(Calculated).
Uniprot: P60660
RRID: AB_2837069

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 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

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Related Downloads
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%)
Clonality:
Polyclonal
Specificity:
MYL6 Antibody detects endogenous levels of total MYL6.
RRID:
AB_2837069
Cite Format: Affinity Biosciences Cat# DF4718, RRID:AB_2837069.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

adult 1; MYH1; MYH1_HUMAN; MYH2; MYH3; MYH4; MYH6; MyHC-2x; MyHC-IIx/d; MYL1; MYL2; MYL3; MYL5; MYL6; Myosin light chain 2 regulatory cardiac slow; Myosin 1; Myosin heavy chain 1; Myosin heavy chain 1 skeletal muscle adult; Myosin heavy chain 2 skeletal muscle adult; Myosin heavy chain 2x; Myosin heavy chain 3 skeletal muscle adult; Myosin heavy chain 4 skeletal muscle adult; Myosin heavy chain 6 skeletal muscle adult; Myosin heavy chain; Myosin heavy chain IIx/d; Myosin heavy chain skeletal muscle adult 1; Myosin II; Myosin light chain 1 alkali skeletal fast; Myosin light chain 3 alkali ventricular skeletal slow; Myosin light chain 4 alkali atrial embryonic; Myosin light chain 5 regulatory; Myosin light chain 6 alkali smooth muscle and non muscle; Myosin-1; Myosin1; skeletal muscle;

Immunogens

Immunogen:
Uniprot:

P60660(MYL6_HUMAN) >>Visit HPA database.

Gene(ID):
MYL6(4637)
Sequence:
MCDFTEDQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDEMNVKVLDFEHFLPMLQTVAKNKDQGTYEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTEEEVEMLVAGHEDSNGCINYEAFVRHILSG

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Rabbit
100
Zebrafish
75
Chicken
75
Dog
0
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P60660 As Substrate

Site PTM Type Enzyme
C2 Acetylation
K13 Ubiquitination
S20 Phosphorylation
R21 Methylation
T22 Phosphorylation
K26 Acetylation
K26 Ubiquitination
Y29 Phosphorylation
S30 Phosphorylation
T44 Phosphorylation
K50 Acetylation
K50 Ubiquitination
K56 Sumoylation
K56 Ubiquitination
S57 Phosphorylation
K63 Ubiquitination
K79 Ubiquitination
K81 Acetylation
K81 Ubiquitination
T85 Phosphorylation
Y86 Phosphorylation
Y89 Phosphorylation
R94 Methylation
K98 Acetylation
K98 Ubiquitination
T103 Phosphorylation
T115 Phosphorylation
T121 Phosphorylation
S135 Phosphorylation
Y141 Phosphorylation

Research Backgrounds

Function:

Regulatory light chain of myosin. Does not bind calcium.

Subunit Structure:

Myosin is a hexamer of 2 heavy chains and 4 light chains. Interacts with SPATA6.

Research Fields

· Cellular Processes > Cellular community - eukaryotes > Tight junction.   (View pathway)

· Organismal Systems > Circulatory system > Vascular smooth muscle contraction.   (View pathway)

· Organismal Systems > Endocrine system > Oxytocin signaling pathway.

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For Research Use Only.
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