FEV Antibody - #DF4675
| Product: | FEV Antibody |
| Catalog: | DF4675 |
| Description: | Rabbit polyclonal antibody to FEV |
| Application: | WB IF/ICC |
| Reactivity: | Human |
| Prediction: | Pig, Bovine, Horse, Sheep, Chicken |
| Mol.Wt.: | 25 KD; 25kD(Calculated). |
| Uniprot: | Q99581 |
| RRID: | AB_2837026 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4675, RRID:AB_2837026.
Fold/Unfold
ETS-domain transcription factor; FEV (ETS oncogene family); FEV; FEV ETS transcription factor; FEV_HUMAN; Fifth Ewing sarcoma variant; Fifth Ewing variant protein; HSRNAFEV; mPet1; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; Pet-1; Protein FEV;
Immunogens
In brain, exclusively expressed in the major serotonergic neurons of the dorsal and median raphe nuclei located in the midbrain and pons. Also detected in prostate and small intestine.
- Q99581 FEV_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRQSGASQPLLINMYLPDPVGDGLFKDGKNPSWGPLSPAVQKGSGQIQLWQFLLELLADRANAGCIAWEGGHGEFKLTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMSKVHGKRYAYRFDFQGLAQACQPPPAHAHAAAAAAAAAAAAQDGALYKLPAGLAPLPFPGLSKLNLMAASAGVAPAGFSYWPGPGPAATAAAATAALYPSPSLQPPPGPFGAVAAASHLGGHYH
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q99581 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K91 | Ubiquitination | Uniprot | |
| Y98 | Phosphorylation | Uniprot | |
| K100 | Ubiquitination | Uniprot |
Research Backgrounds
Functions as a transcriptional regulator. According to it functions as a transcriptional repressor. Functions in the differentiation and the maintenance of the central serotonergic neurons. May play a role in cell growth.
Nucleus.
In brain, exclusively expressed in the major serotonergic neurons of the dorsal and median raphe nuclei located in the midbrain and pons. Also detected in prostate and small intestine.
Belongs to the ETS family.
Research Fields
· Human Diseases > Cancers: Overview > Transcriptional misregulation in cancer.
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