TBPL2 Antibody | Affinity Biosciences

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Western blot analysis of extracts from HeLa cells, using TBPL2 antibody.

DF4661 at 1/100 staining Mouse spleen tissue by IHC-P.

Product:	TBPL2 Antibody
Catalog:	DF4661
Description:	Rabbit polyclonal antibody to TBPL2
Application:	WB IHC IF/ICC
Reactivity:	Human, Mouse
Prediction:	Dog
Mol.Wt.:	41 KD; 42kD(Calculated).
Uniprot:	Q6SJ96
RRID:	AB_2837012

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Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the target protein. By comparing the staining from the blocked antibody versus the antibody alone, one can see which staining is specific.

Size	Price	Inventory
100ul	$280	In stock
200ul	$350	In stock

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Related Downloads

MS Report

HPLC Report

MSDS

Data Sheet

COA

Protocols

WB Handbook

IHC Protocol

IF/ICC Protocol

Product Info

Source:

Rabbit

Application:

WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:

Human,Mouse

Prediction:

Dog(89%)

Clonality:

Polyclonal

Specificity:

TBPL2 Antibody detects endogenous levels of total TBPL2.

RRID:

AB_2837012
Cite Format: Affinity Biosciences Cat# DF4661, RRID:AB_2837012.

Conjugate:

Unconjugated.

Purification:

The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Storage:

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.

Alias:

Fold/Unfold

TATA binding protein 2; TATA box binding protein like 2; TATA box-binding protein-like 2; TATA box-binding protein-like protein 2; TATA box-binding protein-related factor 3; TATA-binding protein 2; TBP related factor 3; TBP-like protein 2; TBP-related factor 3; Tbpl2; TBPL2_HUMAN; TRF3;

Immunogens

Immunogen:

Uniprot:

Q6SJ96(TBPL2_HUMAN) >>Visit HPA database.

Gene(ID):

TBPL2(387332)

Expression:

Q6SJ96 TBPL2_HUMAN:

Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.

Sequence:

Q6SJ96 TBPL2_HUMAN:
Protein BLAST With
NCBI/
ExPASy/
Uniprot

MASAPWPERVPRLLAPRLPSYPPPPPTVGLRSMEQEETYLELYLDQCAAQDGLAPPRSPLFSPVVPYDMYILNASNPDTAFNSNPEVKETSGDFSSVDLSFLPDEVTQENKDQPVISKHETEENSESQSPQSRLPSPSEQDVGLGLNSSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLACKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARVVQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIFVSGKVVLTGAKERSEIYEAFENIYPILKGFKKA

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species

Results

Score

Dog

Pig

Bovine

Sheep

Rabbit

Xenopus

Chicken

Horse

Zebrafish

Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q6SJ96 As Substrate

Q6SJ96

Site	PTM Type	Source
K262	Ubiquitination	Uniprot
S267	Phosphorylation	Uniprot
Y274	Phosphorylation	Uniprot
S344	Phosphorylation	Uniprot

Research Backgrounds

Q6SJ96_TBPL2_HUMAN

Function:

Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity).

Subcellular Location:

Cytoplasm. Nucleus.
Note: Present in the cytoplasm during cytokinesis.

Tissue Specificity:

Ubiquitously expressed in all tissues examined with highest levels in heart, lung, ovary, spleen and testes.

Subunit Structure:

Interacts with TAF3.

Family&Domains:

Belongs to the TBP family.

Research Fields

· Genetic Information Processing > Transcription > Basal transcription factors.

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.

· Human Diseases > Infectious diseases: Viral > HTLV-I infection.

· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.

· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.

· Human Diseases > Cancers: Overview > Viral carcinogenesis.

Restrictive clause

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
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TBPL2 Antibody - #DF4661