RALY Antibody - #DF4657
| Product: | RALY Antibody |
| Catalog: | DF4657 |
| Description: | Rabbit polyclonal antibody to RALY |
| Application: | WB IHC IF/ICC |
| Reactivity: | Human, Mouse, Rat |
| Prediction: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| Mol.Wt.: | 35 KD; 32kD(Calculated). |
| Uniprot: | Q9UKM9 |
| RRID: | AB_2837008 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4657, RRID:AB_2837008.
Fold/Unfold
Autoantigen p542; Heterogeneous nuclear ribonucleoprotein C-like 2; hnRNP associated with lethal yellow protein homolog; hnRNP core protein C-like 2; MGC117312; P542; RALY; RALY_HUMAN; RNA binding protein (autoantigenic hnRNP associated with lethal yellow); RNA binding protein (autoantigenic); RNA binding protein autoantigenic (hnRNP associated with lethal yellow homolog (mouse)); RNA-binding protein Raly;
Immunogens
Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
- Q9UKM9 RALY_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLKLQASNVTNKNDPKSINSRVFIGNLNTALVKKSDVETIFSKYGRVAGCSVHKGYAFVQYSNERHARAAVLGENGRVLAGQTLDINMAGEPKPDRPKGLKRAASAIYSGYIFDYDYYRDDFYDRLFDYRGRLSPVPVPRAVPVKRPRVTVPLVRRVKTNVPVKLFARSTAVTTSSAKIKLKSSELQAIKTELTQIKSNIDALLSRLEQIAAEQKANPDGKKKGDGGGAGGGGGGGGSGGGGSGGGGGGGSSRPPAPQENTTSEAGLPQGEARTRDDGDEEGLLTHSEEELEHSQDTDADDGALQ
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UKM9 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Acetylation | Uniprot | |
| S2 | Phosphorylation | Uniprot | |
| K4 | Methylation | Uniprot | |
| K4 | Sumoylation | Uniprot | |
| K4 | Ubiquitination | Uniprot | |
| K13 | Ubiquitination | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| T30 | Phosphorylation | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| K35 | Ubiquitination | Uniprot | |
| S36 | Phosphorylation | Uniprot | |
| S43 | Phosphorylation | Uniprot | |
| K44 | Acetylation | Uniprot | |
| K44 | Ubiquitination | Uniprot | |
| K55 | Acetylation | Uniprot | |
| K55 | Ubiquitination | Uniprot | |
| Y57 | Phosphorylation | Uniprot | |
| Y62 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| T84 | Phosphorylation | Uniprot | |
| K94 | Ubiquitination | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| S106 | Phosphorylation | Uniprot | |
| Y109 | Phosphorylation | Uniprot | |
| Y112 | Phosphorylation | Uniprot | |
| Y118 | Phosphorylation | Uniprot | |
| Y124 | Phosphorylation | Uniprot | |
| R126 | Methylation | Uniprot | |
| R131 | Methylation | Uniprot | |
| S135 | Phosphorylation | P24941 (CDK2) | Uniprot |
| R141 | Methylation | Uniprot | |
| K146 | Methylation | Uniprot | |
| K146 | Ubiquitination | Uniprot | |
| T151 | Phosphorylation | Uniprot | |
| K159 | Sumoylation | Uniprot | |
| K159 | Ubiquitination | Uniprot | |
| T160 | Phosphorylation | O14757 (CHEK1) | Uniprot |
| K165 | Acetylation | Uniprot | |
| K165 | Sumoylation | Uniprot | |
| K165 | Ubiquitination | Uniprot | |
| S170 | Phosphorylation | Uniprot | |
| T175 | Phosphorylation | Uniprot | |
| S176 | Phosphorylation | Uniprot | |
| S177 | Phosphorylation | Uniprot | |
| K179 | Ubiquitination | Uniprot | |
| K181 | Acetylation | Uniprot | |
| K183 | Acetylation | Uniprot | |
| K183 | Ubiquitination | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| K191 | Ubiquitination | Uniprot | |
| K198 | Ubiquitination | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| K216 | Ubiquitination | Uniprot | |
| S264 | Phosphorylation | Uniprot | |
| T275 | Phosphorylation | Uniprot | |
| T286 | Phosphorylation | Uniprot | |
| S288 | Phosphorylation | Uniprot | |
| S295 | Phosphorylation | Uniprot | |
| T298 | Phosphorylation | Uniprot |
Research Backgrounds
RNA-binding protein that acts as a transcriptional cofactor for cholesterol biosynthetic genes in the liver. Binds the lipid-responsive non-coding RNA LeXis and is required for LeXis-mediated effect on cholesterogenesis (By similarity). May be a heterogeneous nuclear ribonucleoprotein (hnRNP).
Nucleus.
Expressed in heart, brain, lung, liver, skeletal muscle, kidney and pancreas. Weakly expressed in placenta.
Identified in the spliceosome C complex. Interacts (through its RNA-binding domain) with FUS (through its RNA-binding domain); both are components of the same RNPs.
Belongs to the RRM HNRPC family. RALY subfamily.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.