SLC30A4 Antibody - #DF4633
(1)
(4)
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4633, RRID:AB_2836997.
Fold/Unfold
Dri 27 protein; Lethal milk protein; Slc30a4; Solute carrier family 30 (zinc transporter), member 4; Solute carrier family 30 member 4; Zinc transporter 4; ZnT-4; Znt4; ZNT4_HUMAN;
Immunogens
- O14863 ZNT4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGSGAWKRLKSMLRKDDAPLFLNDTSAFDFSDEAGDEGLSRFNKLRVVVADDGSEAPERPVNGAHPTLQADDDSLLDQDLPLTNSQLSLKVDSCDNCSKQREILKQRKVKARLTIAAVLYLLFMIGELVGGYIANSLAIMTDALHMLTDLSAIILTLLALWLSSKSPTKRFTFGFHRLEVLSAMISVLLVYILMGFLLYEAVQRTIHMNYEINGDIMLITAAVGVAVNVIMGFLLNQSGHRHSHSHSLPSNSPTRGSGCERNHGQDSLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPEYKIADPICTYVFSLLVAFTTFRIIWDTVVIILEGVPSHLNVDYIKEALMKIEDVYSVEDLNIWSLTSGKSTAIVHIQLIPGSSSKWEEVQSKANHLLLNTFGMYRCTIQLQSYRQEVDRTCANCQSSSP
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O14863 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S12 | Phosphorylation | Uniprot | |
| K106 | Ubiquitination | Uniprot | |
| S313 | Phosphorylation | Uniprot | |
| S412 | Phosphorylation | Uniprot |
Research Backgrounds
Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.
Endosome membrane>Multi-pass membrane protein. Late endosome membrane>Multi-pass membrane protein. Lysosome membrane>Multi-pass membrane protein.
Contains a histidine-rich region which is a ligand for zinc and an aspartate-rich region which is a potential ligand for zinc.
Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
References
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