CCT6A Antibody - #DF4562

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Product: CCT6A Antibody
Catalog: DF4562
Description: Rabbit polyclonal antibody to CCT6A
Application: WB IHC IF/ICC
Reactivity: Human, Mouse, Rat
Prediction: Bovine, Sheep, Dog, Chicken
Mol.Wt.: 60 KD; 58kD(Calculated).
Uniprot: P40227
RRID: AB_2836913

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Related Downloads
MS Report
HPLC Report
MSDS
Data Sheet
COA
Protocols
WB Handbook
IHC Protocol
IF/ICC Protocol

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human,Mouse,Rat
Prediction:
Bovine(100%), Sheep(100%), Dog(100%), Chicken(100%)
Clonality:
Polyclonal
Specificity:
CCT6A Antibody detects endogenous levels of total CCT6A.
RRID:
AB_2836913
Cite Format: Affinity Biosciences Cat# DF4562, RRID:AB_2836913.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

Acute morphine dependence related protein 2; Amino acid transport defect complementing; CCT zeta 1; CCT zeta; CCT-zeta; CCT-zeta-1; CCT6; CCTZ; Chaperonin containing T complex subunit 6; Chaperonin containing TCP1 subunit 6A; Chaperonin containing TCP1 subunit 6A (zeta 1); Histidine transport regulator 3; HTR3; MGC126214; MGC126215; MoDP 2; MoDP-2; MoDP2; T complex protein 1 subunit zeta; T complex protein 1 zeta subunit; TCP 1 zeta; TCP-1-zeta; TCP1 zeta; TCP20; TCPZ; TTCP20;

Immunogens

Immunogen:
Uniprot:

P40227(TCPZ_HUMAN) >>Visit HPA database.

Gene(ID):
CCT6A(908)
Sequence:
MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIKKQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPFSLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKFTFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG

Predictions

Predictions:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Sheep
100
Dog
100
Chicken
100
Xenopus
70
Zebrafish
70
Pig
0
Horse
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P40227 As Substrate

Site PTM Type Enzyme
A2 Acetylation
K5 Acetylation
K5 Methylation
K5 Ubiquitination
T6 Phosphorylation
K10 Acetylation
K10 Sumoylation
K10 Ubiquitination
R35 Methylation
K41 Ubiquitination
K45 Ubiquitination
K55 Ubiquitination
K58 Ubiquitination
K79 Ubiquitination
T82 Phosphorylation
K104 Ubiquitination
Y109 Phosphorylation
T120 Phosphorylation
K127 Ubiquitination
K129 Ubiquitination
K138 Ubiquitination
K159 Ubiquitination
K180 Ubiquitination
K199 Acetylation
K199 Ubiquitination
S200 Phosphorylation
T204 Phosphorylation
S205 Phosphorylation
Y229 Phosphorylation
Y239 Phosphorylation
K241 Ubiquitination
S246 Phosphorylation
Y250 Phosphorylation
K251 Ubiquitination
K258 Ubiquitination
K265 Ubiquitination
K272 Ubiquitination
K280 Acetylation
K280 Ubiquitination
K287 Acetylation
K287 Ubiquitination
K295 Acetylation
K295 Ubiquitination
S301 Phosphorylation
S306 Phosphorylation
K307 Ubiquitination
R314 Methylation
K365 Acetylation
K365 Ubiquitination
K377 Acetylation
K377 Ubiquitination
K381 Ubiquitination
T383 Phosphorylation
K388 Acetylation
K388 Ubiquitination
R396 Methylation
K399 Ubiquitination
C406 S-Nitrosylation
K424 Ubiquitination
K530 Ubiquitination

Research Backgrounds

Function:

Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. The TRiC complex plays a role in the folding of actin and tubulin (Probable).

Subcellular Location:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Subunit Structure:

Component of the chaperonin-containing T-complex (TRiC), a heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. Interacts with PACRG.

Family&Domains:

Belongs to the TCP-1 chaperonin family.

Restrictive clause

 

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