Product: SFRS2B Antibody
Catalog: DF4543
Description: Rabbit polyclonal antibody to SFRS2B
Application: WB IF/ICC
Reactivity: Human
Mol.Wt.: 32 KD; 32kD(Calculated).
Uniprot: Q9BRL6
RRID: AB_2836894

View similar products>>

   Size Price Inventory
 100ul $280 In stock
 200ul $350 In stock

Lead Time: Same day delivery

For pricing and ordering contact:
Local distributors

Product Info

Source:
Rabbit
Application:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

Reactivity:
Human
Clonality:
Polyclonal
Specificity:
SFRS2B Antibody detects endogenous levels of total SFRS2B.
RRID:
AB_2836894
Cite Format: Affinity Biosciences Cat# DF4543, RRID:AB_2836894.
Conjugate:
Unconjugated.
Purification:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
Storage:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
Alias:

Fold/Unfold

arginine/serine-rich 2B; Pre mRNA splicing factor SRP46; Pre-mRNA-splicing factor SRP46; Serine/arginine-rich splicing factor 8; SFRS2B; Splicing factor; Splicing factor arginine serine rich 46kD; Splicing factor arginine serine rich 2B; Splicing factor SRp46; SRP46; SRSF8; SRSF8_HUMAN;

Immunogens

Immunogen:
Uniprot:
Gene(ID):
Expression:
Q9BRL6 SRSF8_HUMAN:

Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus.

Sequence:
MSCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDGAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSPEEEGQMSS

PTMs - Q9BRL6 As Substrate

Site PTM Type Enzyme
S2 Acetylation
S2 Phosphorylation
T25 Phosphorylation
S26 Phosphorylation
S29 Phosphorylation
R31 Methylation
K36 Acetylation
K36 Ubiquitination
R39 Methylation
Y44 Phosphorylation
S100 Phosphorylation
R106 Methylation
R110 Methylation
S134 Phosphorylation
S136 Phosphorylation
S140 Phosphorylation
S142 Phosphorylation
S144 Phosphorylation
S153 Phosphorylation
Y155 Phosphorylation
S156 Phosphorylation
S158 Phosphorylation
Y160 Phosphorylation
S161 Phosphorylation
S163 Phosphorylation
Y165 Phosphorylation
S166 Phosphorylation
S168 Phosphorylation
Y170 Phosphorylation
S171 Phosphorylation
S173 Phosphorylation
Y175 Phosphorylation
S176 Phosphorylation
S178 Phosphorylation
Y180 Phosphorylation
S188 Phosphorylation
Y190 Phosphorylation
S191 Phosphorylation
S192 Phosphorylation
S196 Phosphorylation
S198 Phosphorylation
S218 Phosphorylation
K233 Methylation
S236 Phosphorylation
S238 Phosphorylation
S240 Phosphorylation
R241 Methylation
T250 Phosphorylation
S252 Phosphorylation
S267 Phosphorylation
S273 Phosphorylation
S281 Phosphorylation
S282 Phosphorylation

Research Backgrounds

Function:

Involved in pre-mRNA alternative splicing.

Subcellular Location:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
Tissue Specificity:

Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus.

Family&Domains:

Belongs to the splicing factor SR family.

Research Fields

· Genetic Information Processing > Transcription > Spliceosome.

· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.