ATP1B3 Antibody - #DF4528
| Product: | ATP1B3 Antibody |
| Catalog: | DF4528 |
| Description: | Rabbit polyclonal antibody to ATP1B3 |
| Application: | WB IF/ICC |
| Reactivity: | Human, Rat |
| Prediction: | Pig, Bovine, Sheep, Rabbit, Dog |
| Mol.Wt.: | 31 KD; 32kD(Calculated). |
| Uniprot: | P54709 |
| RRID: | AB_2836879 |
Related Downloads
Protocols
Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4528, RRID:AB_2836879.
Fold/Unfold
AT1B3_HUMAN; atp1b3; ATPase Na+/K+ transporting beta 3 polypeptide; ATPB 3; ATPB-3; ATPB3; CD 298; CD298; CD298 antigen; FLJ29027; Na K ATPase beta 3 polypeptide; Na+/K+ ATPase beta 3 subunit; NKAB3S; Sodium potassium ATPase subunit beta 3 (non catalytic); Sodium pump subunit beta 3; Sodium/potassium dependent ATPase beta 3 subunit; Sodium/potassium dependent ATPase subunit beta 3; Sodium/potassium transporting ATPase beta 3 chain; Sodium/potassium transporting ATPase subunit beta 3; Sodium/potassium-dependent ATPase subunit beta-3; Sodium/potassium-transporting ATPase subunit beta-3;
Immunogens
- P54709 AT1B3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTKNEKKSLNQSLAEWKLFIYNPTTGEFLGRTAKSWGLILLFYLVFYGFLAALFSFTMWVMLQTLNDEVPKYRDQIPSPGLMVFPKPVTALEYTFSRSDPTSYAGYIEDLKKFLKPYTLEEQKNLTVCPDGALFEQKGPVYVACQFPISLLQACSGMNDPDFGYSQGNPCILVKMNRIIGLKPEGVPRIDCVSKNEDIPNVAVYPHNGMIDLKYFPYYGKKLHVGYLQPLVAVQVSFAPNNTGKEVTVECKIDGSANLKSQDDRDKFLGRVMFKITARA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P54709 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K7 | Ubiquitination | Uniprot | |
| S8 | Phosphorylation | Uniprot | |
| S12 | Phosphorylation | Uniprot | |
| K17 | Ubiquitination | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| T101 | Phosphorylation | Uniprot | |
| S102 | Phosphorylation | Uniprot | |
| Y103 | Phosphorylation | Uniprot | |
| Y106 | Phosphorylation | Uniprot | |
| K111 | Acetylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| K112 | Acetylation | Uniprot | |
| K112 | Ubiquitination | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| K123 | Ubiquitination | Uniprot | |
| K137 | Ubiquitination | Uniprot | |
| K182 | Ubiquitination | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| K220 | Ubiquitination | Uniprot | |
| K221 | Ubiquitination | Uniprot | |
| N240 | N-Glycosylation | Uniprot | |
| K251 | Ubiquitination | Uniprot | |
| K259 | Ubiquitination | Uniprot | |
| K266 | Ubiquitination | Uniprot | |
| K274 | Ubiquitination | Uniprot |
Research Backgrounds
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.
Cell membrane>Single-pass type II membrane protein. Melanosome.
Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit.
The C-terminal lobe folds into an immunoglobulin-like domain and may mediate cell adhesion properties.
Belongs to the X(+)/potassium ATPases subunit beta family.
Research Fields
· Environmental Information Processing > Signal transduction > cGMP-PKG signaling pathway. (View pathway)
· Environmental Information Processing > Signal transduction > cAMP signaling pathway. (View pathway)
· Organismal Systems > Circulatory system > Cardiac muscle contraction. (View pathway)
· Organismal Systems > Circulatory system > Adrenergic signaling in cardiomyocytes. (View pathway)
· Organismal Systems > Endocrine system > Insulin secretion. (View pathway)
· Organismal Systems > Endocrine system > Thyroid hormone synthesis.
· Organismal Systems > Endocrine system > Thyroid hormone signaling pathway. (View pathway)
· Organismal Systems > Endocrine system > Aldosterone synthesis and secretion.
· Organismal Systems > Excretory system > Aldosterone-regulated sodium reabsorption.
· Organismal Systems > Excretory system > Endocrine and other factor-regulated calcium reabsorption.
· Organismal Systems > Excretory system > Proximal tubule bicarbonate reclamation.
· Organismal Systems > Digestive system > Salivary secretion.
· Organismal Systems > Digestive system > Gastric acid secretion.
· Organismal Systems > Digestive system > Pancreatic secretion.
· Organismal Systems > Digestive system > Carbohydrate digestion and absorption.
· Organismal Systems > Digestive system > Protein digestion and absorption.
· Organismal Systems > Digestive system > Mineral absorption.
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