SLC28A2 Antibody - #DF4522
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Product Info
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
Cite Format: Affinity Biosciences Cat# DF4522, RRID:AB_2836873.
Fold/Unfold
CNT 2; CNT2; Concentrative nucleoside transporter 2; FLJ21468; hCNT2; HsT17153; MGC138252; Na(+)/nucleoside cotransporter 2; S28A2_HUMAN; Slc28a2; Sodium coupled nucleoside transporter 2; Sodium-coupled nucleoside transporter 2; Sodium/nucleoside cotransporter 2; Sodium/purine nucleoside co transporter; Sodium/purine nucleoside co-transporter; Solute carrier family 28 (sodium coupled nucleoside transporter) member 2; Solute carrier family 28 member 2; SPNT; SPNT1;
Immunogens
Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.
- O43868 S28A2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEKASGRQSIALSTVETGTVNPGLELMEKEVEPEGSKRTDAQGHSLGDGLGPSTYQRRSRWPFSKARSFCKTHASLFKKILLGLLCLAYAAYLLAACILNFQRALALFVITCLVIFVLVHSFLKKLLGKKLTRCLKPFENSRLRLWTKWVFAGVSLVGLILWLALDTAQRPEQLIPFAGICMFILILFACSKHHSAVSWRTVFSGLGLQFVFGILVIRTDLGYTVFQWLGEQVQIFLNYTVAGSSFVFGDTLVKDVFAFQALPIIIFFGCVVSILYYLGLVQWVVQKVAWFLQITMGTTATETLAVAGNIFVGMTEAPLLIRPYLGDMTLSEIHAVMTGGFATISGTVLGAFIAFGVDASSLISASVMAAPCALASSKLAYPEVEESKFKSEEGVKLPRGKERNVLEAASNGAVDAIGLATNVAANLIAFLAVLAFINAALSWLGELVDIQGLTFQVICSYLLRPMVFMMGVEWTDCPMVAEMVGIKFFINEFVAYQQLSQYKNKRLSGMEEWIEGEKQWISVRAEIITTFSLCGFANLSSIGITLGGLTSIVPHRKSDLSKVVVRALFTGACVSLISACMAGILYVPRGAEADCVSFPNTSFTNRTYETYMCCRGLFQSTSLNGTNPPSFSGPWEDKEFSAMALTNCCGFYNNTVCA
Predictions
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O43868 As Substrate
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y55 | Phosphorylation | Uniprot | |
| K78 | Methylation | Uniprot | |
| K79 | Methylation | Uniprot | |
| S377 | Phosphorylation | Uniprot | |
| K396 | Ubiquitination | Uniprot |
Research Backgrounds
Sodium-dependent and purine-selective transporter. Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine). Plays a critical role in specific uptake and salvage of purine nucleosides in kidney and other tissues.
Membrane>Multi-pass membrane protein.
Expressed in heart and skeletal muscle followed by liver, kidney, intestine, pancreas, placenta and brain. Weak expression in lung.
Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
References
Application: WB Species: mouse Sample: hippocampus
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